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经皮腔内冠状动脉成形术(PTCA)在冠心病治疗中的应用

[Percutaneous transluminal coronary angioplasty (PTCA) in the therapy of coronary heart disease].

作者信息

Klein W

机构信息

Medizinischen Universitätsklinik Graz.

出版信息

Acta Med Austriaca. 1988;15(2):57-60.

PMID:2970201
Abstract

Percutaneous transluminal angioplasty (PTCA) has been performed worldwide since 10 years and in Graz since 1980. 1977 6 procedures were performed, 1987 about 100,000 will be done worldwide. PTCA today represents a standard treatment of coronary heart disease in addition to pharmacological and surgical therapy. At the present time about one third of patients with coronary heart disease are treated by PTCA. Primary success rate ranges between 80 and 90%, complication rate has dropped under 4%. Besides patients with one-vessel-disease also those with multi-vessel-disease, reduced left ventricular function and patients with unstable angina and acute myocardial infarction are dilated. The "achilles" heel of PTCA is restenosis, which develops in 25 to 35% of cases within 6 months. At present, research is devoted to avoid or prevent this complication.

摘要

经皮腔内血管成形术(PTCA)自10年前起已在全球范围内开展,自1980年起在格拉茨开展。1977年进行了6例手术,到1987年全球预计将进行约10万例。如今,PTCA除了药物治疗和手术治疗外,已成为冠心病的标准治疗方法。目前,约三分之一的冠心病患者接受PTCA治疗。主要成功率在80%至90%之间,并发症发生率已降至4%以下。除了单支血管病变的患者外,多支血管病变、左心室功能减退以及不稳定型心绞痛和急性心肌梗死的患者也接受扩张治疗。PTCA的“致命弱点”是再狭窄,在6个月内25%至35%的病例中会出现。目前,研究致力于避免或预防这种并发症。

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