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尼日利亚一家医院抗逆转录病毒治疗期间患者报告的生活质量

Patient-Reported Quality of Life During Antiretroviral Therapy in a Nigerian Hospital.

作者信息

Oparah Azuka C, Soni Jeffrey S, Arinze Herbert I, Chiazor Ifeanyi E

机构信息

Department of Clinical Pharmacy and Pharmacy Practice, University of Benin, 300001, Benin City, Nigeria.

Department of Clinical Pharmacy and Pharmacy Practice, University of Benin, 300001, Benin City, Nigeria.

出版信息

Value Health Reg Issues. 2013 Sep-Oct;2(2):254-258. doi: 10.1016/j.vhri.2013.07.004. Epub 2013 Sep 13.

DOI:10.1016/j.vhri.2013.07.004
PMID:29702873
Abstract

OBJECTIVES

We assessed the reported quality of life of patients with HIV/AIDS and explored the impact of patients' sociodemographic profile on the quality-of-life domains.

METHODS

Consenting outpatients who met criteria were consecutively selected in a secondary health care facility in Benin City, Nigeria. Quality of life was determined in the nine domains of HIV/AIDS Targeted Quality of Life (HAT-QOL) instrument. Quality-of-life scores were computed on the scale of 0 to 100 and triangulated with a rated interval scale of 1 to 5 suited for quantitative analysis. Association between rated scores and each domain was explored by using Students' t test and analysis of variance at 95% confidence interval.

RESULTS

Out of the 403 patients, 82.1% were females; 147 (36.1%) belonged to the modal age group of 20 to 30 years; the mean age for grouped data was 39.2 years. About 239 (58.7%) were not married. Also, 338 (83.0%) earned below $1500 per annum and 303 (74.40%) had basic education (grade 1 to grade 9). HAT-QOL scores indicated the following: overall function (89.96 ± 5.62); life satisfaction (91.94 ± 3.62); health worries (87.06 ± 4.28); financial worries (81.00 ± 3.95); medication worries (91.65 ± 4.47); HIV mastery (71.00 ± 3.11); disclosure worries (27.50 ± 7.57); provider trust (91.63 ± 1.96); and sexual function (70.25 ± 3.51). Likert-type rated scores were in agreement with HAT-QOL scores. Provider trust was associated with gender, employment status, and educational level. Sexual function was associated with gender and age (P < 0.05).

CONCLUSIONS

Patients reported satisfactory quality of life in the domains of overall function, life satisfaction, health worries, financial worries, medication worries, HIV mastery, provider trust, and sexual function. Quality of life was low in the domain of disclosure worries, indicating concerns for discrimination and stigmatization. Age, level of education, and employment status had a strong impact on the quality of life of patients with HIV/AIDs.

摘要

目的

我们评估了报告的艾滋病毒/艾滋病患者的生活质量,并探讨了患者社会人口学特征对生活质量领域的影响。

方法

在尼日利亚贝宁城的一家二级医疗保健机构中,连续挑选出符合标准且同意参与的门诊患者。通过艾滋病毒/艾滋病针对性生活质量(HAT-QOL)工具的九个领域来确定生活质量。生活质量得分在0至100的量表上计算,并与适合定量分析的1至5的等级间隔量表进行三角测量。使用学生t检验和95%置信区间的方差分析来探讨等级得分与每个领域之间的关联。

结果

在403名患者中,82.1%为女性;147名(36.1%)属于20至30岁的典型年龄组;分组数据的平均年龄为39.2岁。约239名(58.7%)未婚。此外,338名(83.0%)的年收入低于1500美元,303名(74.40%)接受过基础教育(1年级至9年级)。HAT-QOL得分如下:总体功能(89.96±5.62);生活满意度(91.94±3.62);健康担忧(87.06±4.28);经济担忧(81.00±3.95);药物担忧(91.65±4.47);对艾滋病毒的掌控感(71.00±3.11);披露担忧(27.50±7.57);对医疗服务提供者的信任(91.63±1.96);以及性功能(70.25±3.51)。李克特式等级得分与HAT-QOL得分一致。对医疗服务提供者的信任与性别、就业状况和教育水平相关。性功能与性别和年龄相关(P<0.05)。

结论

患者在总体功能、生活满意度、健康担忧、经济担忧、药物担忧、对艾滋病毒的掌控感、对医疗服务提供者的信任和性功能等领域报告了令人满意的生活质量。在披露担忧领域,生活质量较低,表明存在对歧视和污名化的担忧。年龄、教育水平和就业状况对艾滋病毒/艾滋病患者的生活质量有很大影响。

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