Kalliainen Loree K, Wisecarver Ian, Cummings Allison, Stone Jennifer
Division of Plastic and Hand Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC.
Division of Plastic and Hand Surgery, Department of Surgery, University of North Carolina, Chapel Hill, NC.
J Hand Surg Am. 2018 Nov;43(11):1026-1029. doi: 10.1016/j.jhsa.2018.03.026. Epub 2018 Apr 24.
It has been long recognized that sex-based biases related to participant inclusion exist in research. To help address inequities in research participation, the National Institutes of Health Revitalization Act was passed into law in 1993. Although this act was primarily designed to increase inclusion of females and minorities in research funded by National Institutes of Health, it has also helped raise global awareness of the value of routinely including females and minority groups in research. Subsequent work has demonstrated a continued gap in inclusion of females in medical and surgical research and female animals and cell lines in basic science research. Hand surgeons have recognized that certain conditions have greater incidence in one sex over the other, but there has been no widespread discussion on whether, when, and how sex should be used as an outcomes variable. This review investigated the recent hand surgery literature to assess for equity in inclusion of both sexes in research as well as whether outcomes were analyzed based on sex.
长期以来，人们已经认识到研究中存在与参与者纳入相关的性别偏见。为了帮助解决研究参与方面的不平等问题，1993年《国立卫生研究院振兴法案》被通过成为法律。尽管该法案主要旨在增加国立卫生研究院资助的研究中女性和少数群体的纳入，但它也有助于提高全球对在研究中常规纳入女性和少数群体的价值的认识。后续工作表明，在医学和外科研究中女性的纳入以及基础科学研究中雌性动物和细胞系的纳入方面仍存在差距。手外科医生已经认识到某些疾病在一种性别中的发病率高于另一种性别，但对于是否、何时以及如何将性别用作结果变量，尚未进行广泛讨论。本综述调查了近期的手外科文献，以评估研究中两性纳入的公平性以及结果是否按性别进行分析。
