Fisher & Paykel Healthcare Ltd, 15 Maurice Paykel Pl, East Tamaki, Auckland, 2013, New Zealand.
Department of Engineering Science, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Ann Biomed Eng. 2018 Aug;46(8):1101-1111. doi: 10.1007/s10439-018-2034-6. Epub 2018 Apr 27.
The primary source of infections in open surgeries has been found to be bacteria and viruses carried into the surgical wound on the surfaces of skin particles shed by patients and surgical staff. In open cardiac surgeries, insufflation of the wound with carbon dioxide is used to limit the quantity of air able to enter into the heart, avoiding air embolisms when the heart is restarted. This surgical technique has been evaluated as a method of limiting the number of skin particles able to enter into the wound, using computational fluid dynamics (CFD) simulations and experimental testing. Spherical particles of 5.0 and 13.5 μm in diameter were used to simulate skin particles falling above a wound, travelling in air ventilation velocities of either 0.2 or 0.4 m/s, and with or without CO insufflation. The CFD simulations with CO included a diffuser placed in the wound and supplied with CO at a rate of 10 L/min. Experimental testing was completed under similar conditions. The results of CFD simulations and experimental testing showed CO insufflation can significantly limit the number of particles able to enter into the wound.
在开放性手术中，感染的主要来源已被发现是细菌和病毒，它们携带在患者和手术人员脱落的皮肤颗粒表面的物质上，并进入手术伤口。在开放性心脏手术中，向伤口内吹入二氧化碳以限制能够进入心脏的空气量，从而避免心脏重新启动时出现空气栓塞。已经使用计算流体动力学（CFD）模拟和实验测试评估了这种手术技术，以限制进入伤口的皮肤颗粒数量。使用直径为 5.0 和 13.5μm 的球形颗粒模拟落在伤口上方的皮肤颗粒，在 0.2 或 0.4m/s 的空气通风速度下移动，并且有或没有 CO 吹入。带有 CO 的 CFD 模拟包括放置在伤口中的扩散器，并以 10L/min 的速率供应 CO。在类似的条件下完成了实验测试。CFD 模拟和实验测试的结果表明，CO 吹入会显著限制能够进入伤口的颗粒数量。
