多重检测时代的疫苗反应测量

Measuring Vaccine Responses in the Multiplex Era.

作者信息

Ayling Kieran, Vedhara Kavita, Fairclough Lucy

机构信息

Division of Primary Care, School of Medicine, University of Nottingham, Nottingham, UK.

School of Life Science, University of Nottingham, Nottingham, UK.

出版信息

Methods Mol Biol. 2018;1781:327-340. doi: 10.1007/978-1-4939-7828-1_17.

DOI:10.1007/978-1-4939-7828-1_17

PMID:29705855

Abstract

Vaccine studies in psychoneuroimmunology (PNI) provide an insight into biopsychosocial interactions and their role in infectious diseases. How to measure vaccine responses is therefore of critical importance for PNI researchers. In this chapter, traditional and modern immunoassays for the assessment of vaccine responses are discussed, highlighting how modern multiplex techniques provide researchers with greater capacity and opportunity for novel research relating to vaccine outcomes.

摘要

精神神经免疫学（PNI）中的疫苗研究有助于深入了解生物心理社会相互作用及其在传染病中的作用。因此，如何测量疫苗反应对于PNI研究人员至关重要。在本章中，将讨论用于评估疫苗反应的传统和现代免疫测定方法，重点介绍现代多重技术如何为研究人员提供与疫苗结果相关的新研究的更大能力和机会。