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[从人和动物中分离出的具有Hsw1N1抗原结构的甲型流感病毒血凝素的比较特征]

[Comparative characteristics of hemagglutinins of influenza A viruses with antigenic structure Hsw1N1 isolated from man and animals].

作者信息

Dem'ianenko I V, Shilov A A, Chuvakova Z K, Chaĭka O V, Isaeva E I

出版信息

Vopr Virusol. 1988 Mar-Apr;33(2):157-62.

PMID:2970717
Abstract

Competitive radioimmunoassay was used to study the antigenic composition of hemagglutinin of Hsw1N1 viruses isolated from man in comparison with hemagglutinin Hsw1 of influenza virus of swine and ducks. The data of oligonucleotide analysis of the 4th RNA segment coding for hemagglutinin in these viruses are presented. It has been shown that in Alma-Ata, 1984-1985, influenza viruses Hsw1N1 were isolated with the antigenic structure of hemagglutinin and with the hemagglutinin gene identical with those of the classical influenza virus of swine A/Swine/Iowa/15/30 but differing from virus A/New Jersey/8/76.

摘要

采用竞争性放射免疫测定法,对从人类分离出的Hsw1N1病毒血凝素的抗原组成进行了研究,并与猪和鸭流感病毒的血凝素Hsw1进行了比较。文中给出了这些病毒中编码血凝素的第4个RNA片段的寡核苷酸分析数据。结果表明,1984 - 1985年在阿拉木图分离出的Hsw1N1流感病毒,其血凝素的抗原结构和血凝素基因与猪A/Swine/Iowa/15/30经典流感病毒相同,但与A/New Jersey/8/76病毒不同。

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