Shintani Yasushi, Hasegawa Seiki, Takuwa Teruhisa, Aoe Keisuke, Kato Katsuya, Fujimoto Nobukazu, Hida Yasuhiro, Morise Masahiro, Moriya Yasumitsu, Morohoshi Takao, Okumura Meinoshin, Yoshino Ichiro
Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Thoracic Surgery, Hyogo College of Medicine, Hyogo, Japan.
J Thorac Dis. 2018 Mar;10(3):1968-1971. doi: 10.21037/jtd.2018.03.53.
The International Association for the Study of Lung Cancer, in collaboration with members of the International Mesothelioma Interest Group (IMIG), developed a large international database and TNM-based system to study malignant pleural mesothelioma (MPM). However, this database has some limitations since it was a retrospective study and it was based predominantly on surgical cases. The Japanese Joint Committee of Lung Cancer Registry (JJCLCR) employs a project of prospective registry database of patients in Japan with MPM in order to clarify MPM's epidemiology, current management practices, and prognosis and also to investigate the potential capabilities to target the best patients for therapy.
Tumor stage is described using the 7th and 8th versions of IMIG staging system. This prospective cohort study has been conducted from April 1, 2017 to March 31, 2019.
We will analyze the data in this registry to determine the most recent outcomes and trends related to MPM treatment in Japan. The present prospective study is expected to validate the 8th version of IMIG staging system, and to investigate whether tumor thickness is a reliable T-descriptor.
ClinicalTrials.gov Identifier: UMIN 000024664.
国际肺癌研究协会与国际间皮瘤利益集团（IMIG）的成员合作，开发了一个大型国际数据库和基于TNM的系统来研究恶性胸膜间皮瘤（MPM）。然而，该数据库存在一些局限性，因为它是一项回顾性研究，且主要基于手术病例。日本肺癌登记联合委员会（JJCLCR）开展了一个针对日本MPM患者的前瞻性登记数据库项目，以阐明MPM的流行病学、当前管理实践和预后，并研究针对最佳治疗患者的潜在能力。
使用IMIG分期系统的第7版和第8版描述肿瘤分期。这项前瞻性队列研究于2017年4月1日至2019年3月31日进行。
我们将分析该登记处的数据，以确定日本MPM治疗的最新结果和趋势。目前的前瞻性研究有望验证IMIG分期系统的第8版，并研究肿瘤厚度是否是一个可靠的T描述符。
ClinicalTrials.gov标识符：UMIN 000024664。
