Sachdeva Uma M, Lanuti Michael
Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Ann Cardiothorac Surg. 2018 Mar;7(2):217-226. doi: 10.21037/acs.2018.03.05.
Cervical exenteration is a radical procedure for the treatment of locally invasive cancers of the trachea, esophagus, or thyroid, as well as recurrent tumors at the site of a tracheal stoma, and occasionally for benign disease. Exenteration involves removal of the larynx, pharynx, esophagus, and trachea, as well as associated lymphatic tissue. The tracheal stump is brought up as a cervical or mediastinal tracheostomy, depending on the length and the location of the distal resection site. The alimentary tract can be reconstructed with several types of conduits, but most commonly the stomach or left colon are used. Tension on the innominate artery must be avoided when repositioning the trachea to prevent innominate artery erosion. Tension on the artery can be addressed by either dividing the vessel or by transposing the trachea inferior and lateral to the innominate artery and vein. Overall, cervical exenteration is associated with a significant risk of morbidity, including anastomotic leak, innominate artery erosion, and tracheostomy dehiscence with subsequent mediastinitis, as well as the potential for postoperative death. Nevertheless, in highly selected patients, it can provide an unparalleled opportunity for either cure or palliation, with functional results equivalent to that of total laryngectomy.
颈部脏器清除术是一种根治性手术,用于治疗气管、食管或甲状腺的局部浸润性癌症,以及气管造口部位的复发性肿瘤,偶尔也用于良性疾病。脏器清除术包括切除喉、咽、食管和气管以及相关的淋巴组织。根据远端切除部位的长度和位置,将气管残端提升为颈部或纵隔气管造口。消化道可以用几种类型的管道进行重建,但最常用的是胃或左结肠。重新定位气管时必须避免无名动脉受到张力,以防止无名动脉侵蚀。可以通过切断血管或将气管移位到无名动脉和静脉的下方及外侧来解决动脉的张力问题。总体而言,颈部脏器清除术伴有显著的发病风险,包括吻合口漏、无名动脉侵蚀、气管造口裂开及随后的纵隔炎,以及术后死亡的可能性。然而,在经过严格挑选的患者中,它可以为治愈或缓解提供无与伦比的机会,功能结果与全喉切除术相当。