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[家族性恶性黑色素瘤及其与发育异常痣综合征的关系:6例临床病例分析]

[Familial malignant melanoma and its relation to dysplastic nevus syndrome: considerations on 6 clinical cases].

作者信息

Ghillani M, Caleffi E

机构信息

Università degli Studi di Parma, Facoltà di Medicina e Chirurgia, Cattedra di Chirurgia Plastica.

出版信息

Acta Biomed Ateneo Parmense. 1987;58(5-6):171-80.

PMID:2970758
Abstract

Two cases of familial expression of malignant melanoma are presented, with regard to three patients recently operated on for this neoplasm. The authors review the literature existing on this subject and make important comments about some hereditary factors probably predisposing to malignant melanoma; among these characteristics are the pigmentary traits of skin, adnexa and iris, the so-called "dysplastic" or "atypical" moles, the cutaneous sensitivity to the sun.

摘要

本文报告了两例恶性黑色素瘤的家族性病例,涉及最近因该肿瘤接受手术的三名患者。作者回顾了关于这一主题的现有文献,并对一些可能易患恶性黑色素瘤的遗传因素发表了重要评论;这些特征包括皮肤、附属器和虹膜的色素性状,所谓的“发育异常”或“非典型”痣,以及皮肤对阳光的敏感性。

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