Controlling CO -Responsive Behaviors of Polymersomes Self-Assembled by Coumarin-Containing Star Polymer via Regulating Its Crosslinking Pattern.

An oligo(ethylene glycol)-based star polymer of N -(OEG-C) with fluorescent coumarin as hydrophobic end groups and dual tertiary amines as the star center is designed and synthesized. Owing to its amphiphilic nature of N -(OEG-C) , it will self-assemble into hollow vesicles with coumarin groups dispersed in the hydrophobic membrane and exhibits CO -responsive behavior due to the protonation of amine centers with CO . More importantly, coumarin moieties can either form non-crosslinking with γ-cyclodextrin via the 2/1 host-guest inclusion, or covalently photodimerized by 365 nm light, offering a tunable crosslinking pattern in the hydrophobic membrane and thus adjusting its CO -stimulated reorganization and disassembly behaviors of these vesicles in aqueous solution.