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[中风后康复期间异常肌肉耦合分析]

[Analysis of Abnormal Muscular Coupling During Rehabilitation after Stroke].

作者信息

Xie Ping, Song Yan, Guo Zihui, Chen Xiaoling, Wu Xiaoguang, Su Yuping, Du Yihao

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2016 Apr;33(2):244-54.

Abstract

For the questions of deeply researching abnormal neuromuscular coupling and better evaluating motor function of stroke patients with motor dysfunction,an effective intermuscular coherence analysis method and index are studied to explore the neuromuscular oscillation and the pathomechanism of motor dysfunction,based on which an assessment standard of muscle function is established.Firstly,the contrastive analysis about the intermuscular coherence of antagonistic muscle of affected and intact upper limbs of stroke patients was conducted.Secondly,a significant indicator of Fisher’s Z-transformed coherence significant indicator was defined to quantitatively describe the coupling differences in certain functional frequency domain between surface electromyogram(sEMG)of affected and intact sides.Further more,the relationship between intermuscular coherence and motor task was studied.Through the analysis of intermuscular coherence during elbow flexion-extension of affected and intact sides,we found that the intermuscular coherence was associated with motor task and the stroke patients exhibited significantly lower betaband intermuscular coherence in performing the task with their affected upper limbs.More conclusion can be drawn that beta-band intermuscular coherence has been found concerned with Fugle-Meyer scale,which indicates that betaband intermuscular coherence could be an index assisting in evaluating motor function of patients.

摘要

针对深入研究异常神经肌肉耦合以及更好地评估存在运动功能障碍的中风患者运动功能的问题,研究了一种有效的肌间相干分析方法和指标,以探究神经肌肉振荡及运动功能障碍的发病机制,并在此基础上建立肌肉功能评估标准。首先,对中风患者患侧和健侧上肢拮抗肌的肌间相干性进行对比分析。其次,定义了一种显著指标——费舍尔Z变换相干显著指标,以定量描述患侧和健侧表面肌电图(sEMG)在特定功能频域内的耦合差异。此外,还研究了肌间相干性与运动任务之间的关系。通过对患侧和健侧肘部屈伸过程中的肌间相干性分析,我们发现肌间相干性与运动任务相关,且中风患者在使用患侧上肢执行任务时,其β频段肌间相干性显著降低。还可得出更多结论,即已发现β频段肌间相干性与Fugle-Meyer量表相关,这表明β频段肌间相干性可作为辅助评估患者运动功能的指标。

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