Zhang Haowei, Zhou Siyuan, Liu Ying, Liang Zhen
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2016 Apr;33(2):268-73.
Computational fluid dynamics was used to investigate the effect of the pathogenesis of membranous obstruction of inferior vena cava of Budd-Chiari syndrome with various angles between right hepatic vein and inferior vena cava.Mimics software was used to reconstruct the models from magnetic resonance imaging(MRI)angiograms of inferior vena cava,right hepatic vein,middle hepatic vein and left hepatic vein,and 3DMAX was used to construct the models of 30°,60°,90°and 120°angles between right hepatic vein and inferior vena cava,which was based on the reconstructed models.The model was conducted with clinical parameters in terms of wall shear stress distribution,static pressure distribution and blood velocity.The results demonstrated that the differences between wall shear stress and static pressure had statistical significance with various angles between right hepatic vein and inferior vena cava by SPSS.The pathogenesis of membranous obstruction of inferior vena cava had a correlation with the angles between right hepatic vein and inferior vena cava.
采用计算流体动力学方法，研究布加综合征下腔静脉膜性梗阻的发病机制与右肝静脉和下腔静脉之间不同夹角的关系。利用Mimics软件，根据下腔静脉、右肝静脉、中肝静脉和左肝静脉的磁共振成像（MRI）血管造影重建模型，并基于重建模型，使用3DMAX构建右肝静脉与下腔静脉夹角为30°、60°、90°和120°的模型。对模型进行壁面剪应力分布、静压分布和血流速度等临床参数分析。结果经SPSS分析表明，右肝静脉与下腔静脉不同夹角下的壁面剪应力和静压差异具有统计学意义。下腔静脉膜性梗阻的发病机制与右肝静脉和下腔静脉之间的夹角有关。
