Nethercott J R, Holness D L
Department of Occupational and Environmental Health, St. Michael's Hospital, University of Toronto, Canada.
Contact Dermatitis. 1988 May;18(5):263-7. doi: 10.1111/j.1600-0536.1988.tb02830.x.
84 funeral service workers and 38 control workers were evaluated for the presence of skin disease by history, clinical examination and patch tests with formaldehyde and glutaraldehyde. No relationship between either personal or family history of cutaneous or respiratory manifestations of atopy and clinical parameters of cutaneous disease or patch test results was found. Cutaneous disease was reported in apprentices, active embalmers and inactive embalmers in decreasing order of frequency. Positive patch test reactions to formaldehyde and glutaraldehyde were found in 4% and 7% of the exposed workers, but in none of the controls. Although exposure to glutaraldehyde was less frequent, the prevalence of positive patch test reactions did not differ. This may suggest that glutaraldehyde poses a greater practical risk of cutaneous sensitization in this trade than formaldehyde.
通过病史、临床检查以及使用甲醛和戊二醛进行斑贴试验，对84名丧葬服务人员和38名对照人员进行了皮肤病检查。未发现特应性皮炎的皮肤或呼吸道表现的个人或家族病史与皮肤病临床参数或斑贴试验结果之间存在关联。据报告，学徒、在职防腐师和非在职防腐师中皮肤病的发生率呈递减顺序。在4%的接触工人中发现对甲醛的斑贴试验反应呈阳性，7%的接触工人对戊二醛的斑贴试验反应呈阳性，但对照组中均未出现阳性反应。尽管接触戊二醛的频率较低，但斑贴试验阳性反应的发生率并无差异。这可能表明，在该行业中，戊二醛比甲醛对皮肤致敏构成更大的实际风险。
