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心内膜消融治疗起源于左心室基底下间隔过程的室性异位搏动。

Endocardial ablation of ventricular ectopic beats arising from the basal inferoseptal process of the left ventricle.

机构信息

Cardiology Clinical Academic Group, St. George's University of London, London, United Kingdom.

UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA, Los Angeles, California.

出版信息

Heart Rhythm. 2018 Sep;15(9):1356-1362. doi: 10.1016/j.hrthm.2018.04.029. Epub 2018 Apr 28.

Abstract

BACKGROUND

Idiopathic ventricular ectopy (VE) shows predilection to sites within the left ventricular (LV) base such as the outflow tract/aortic sinuses, LV summit, and areas adjacent to the aortomitral continuity. We characterize VE arising from the inferior septum of the LV base that was successfully managed by LV endocardial ablation from the inferoseptal recess of the LV.

OBJECTIVE

The purpose of this study was to determine the incidence, electrocardiographic (ECG) findings, electrophysiological findings, and anatomical features associated with VE arising from the basal inferoseptal process of the LV (ISP-LV) ablated using an LV endocardial approach via the inferoseptal recess of the LV.

METHODS

A total of 425 consecutive patients undergoing VE ablation between January 1, 2012 and December 31, 2016 at 3 centers were evaluated. Demographic characteristics, ECG findings, and procedural data were analyzed for patients with ISP-LV VEs.

RESULTS

Seven (1.5%) had a site of origin from the ISP-LV. Common ECG findings were a right bundle branch block concordant pattern or an atypical left bundle branch block early transition pattern, suggestive of a basal origin with a left superior axis, a biphasic QRS complex in lead aVR, and a small s wave in lead V. Earliest activation was seen in an area below the outflow tract accessed from the inferoseptal recess inferior to the His bundle. In 3 cases, transient junctional rhythm was seen during ablation. All cases were ablated successfully with no complications.

CONCLUSION

VE arising from the ISP-LV represents a distinct subset of idiopathic arrhythmia and can be successfully treated by endocardial catheter ablation from the inferoseptal recess. They share common surface ECG and electrophysiological findings with special anatomical features that need recognition for successful catheter ablation.

摘要

背景

特发性室性早搏(VE)倾向于左心室(LV)基底的部位,如流出道/主动脉窦、LV 心尖和主动脉瓣二尖瓣连续区附近。我们描述了起源于 LV 基底下间隔的 VE,通过 LV 心尖下间隔隐窝进行 LV 心内膜消融成功治疗了这些 VE。

目的

本研究的目的是确定通过 LV 心尖下间隔隐窝进行 LV 心内膜消融治疗起源于 LV 基底下间隔(ISP-LV)的 VE 的发生率、心电图(ECG)表现、电生理表现和解剖特征。

方法

对 2012 年 1 月 1 日至 2016 年 12 月 31 日在 3 个中心接受 VE 消融治疗的 425 例连续患者进行评估。分析了 ISP-LV VE 患者的人口统计学特征、心电图表现和程序数据。

结果

7 例(1.5%)起源于 ISP-LV。常见的心电图表现为右束支传导阻滞一致模式或非典型左束支传导阻滞早期过渡模式,提示起源于基底,左上方轴,aVR 导联双相 QRS 复合体和 V 导联小 s 波。最早的激活出现在希氏束下方下间隔隐窝从下至上进入的流出道下方区域。在 3 例中,消融过程中出现短暂的交界性节律。所有病例均成功消融,无并发症。

结论

起源于 ISP-LV 的 VE 代表一种特发性心律失常的独特亚群,可以通过心内膜导管消融从下间隔隐窝成功治疗。它们具有共同的体表 ECG 和电生理表现,具有特殊的解剖特征,需要识别以实现成功的导管消融。

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