(-)-四唑霉素的全合成及其立体化学的测定。
Total Synthesis of (-)-Tetrazomine and Determination of Its Stereochemistry.
作者信息
Scott Jack D, Williams Robert M
机构信息
Department of Chemistry Colorado State University Fort Collins, CO 80523 (USA) Fax: (+1) 970-491-3944.
出版信息
Angew Chem Int Ed Engl. 2001 Apr 17;40(8):1463-1465. doi: 10.1002/1521-3773(20010417)40:8<1463::AID-ANIE1463>3.0.CO;2-8.
Abstract
A new method for the formation of the allylic amine precursor to an azomethine ylide 1 has been developed and exploited in an efficient 1,3-dipolar cycloaddition to afford the key tetracyclic intermediate used in the synthesis of (-)-tetrazomine (2). Bn=benzyl.
摘要
已开发出一种形成甲亚胺叶立德1的烯丙胺前体的新方法，并将其用于高效的1,3-偶极环加成反应，以得到用于合成（-）-四唑明（2）的关键四环中间体。Bn = 苄基。
Zotero 插件