M L V Sai Krishna, Sharma Deep, Menon Jagdish
Department of Orthopaedics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Asian Spine J. 2018 Apr;12(2):277-284. doi: 10.4184/asj.2018.12.2.277. Epub 2018 Apr 16.
This was a prospective, two-group comparative study.
The present study aimed to determine the importance of the spinopelvic parameters in the causation and progression of spondylolisthesis.
Spondylolisthesis is slippage of one vertebra over the vertebra below. Since the discovery of pelvic incidence (PI) in 1998 in addition to documentation of other parameters in spinopelvic balance, slippage in spondylolisthesis has been attributed to these parameters. Many studies on the Caucasian population have implicated high PI as a causative factor of spondylolisthesis. To the best of our knowledge, no study has described the role of these parameters in the progression of spondylolisthesis.
The study was conducted in Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India. Seventy-nine patients with spondylolisthesis consented to participate in the study. All patients were advised to undergo conservative treatment and were regularly followed up according to the protocol. Seventy-five asymptomatic volunteers were recruited as a control group. Of the total of 79 patients, 54 were followed up for 6 months, during which 46 improved, eight showed no improvement, and 25 were lost to follow-up. Sagittal spinopelvic parameters were measured by a single observer using the Surgimap spine software ver. 2.1.2 (Nemaris, New York, NY, USA). Parameters measured were PI, pelvic tilt (PT), sacral slope (SS), thoracic kyphosis, and lumbar lordosis. The results from patients and controls were compared using appropriate statistical methods.
The normal and spondylolisthesis groups significantly differed with respect to PI, SS, and PT (<0.001). There were no significant differences in the measured spinopelvic parameters between patients with high- and low-grade spondylolisthesis or between those whose condition improved and those whose condition worsened.
PI, the most important of all spinopelvic parameters, is responsible for the slip in spondylolisthesis, but not for its progression.
这是一项前瞻性的两组对比研究。
本研究旨在确定脊柱骨盆参数在腰椎滑脱病因及病情进展中的重要性。
腰椎滑脱是指一个椎体在其下方椎体上发生滑移。自1998年发现骨盆入射角(PI)以及记录了脊柱骨盆平衡的其他参数以来,腰椎滑脱中的椎体滑移一直被归因于这些参数。许多针对白种人群的研究表明高PI是腰椎滑脱的一个致病因素。据我们所知,尚无研究描述这些参数在腰椎滑脱病情进展中的作用。
本研究在印度本地治里的贾瓦哈拉尔研究生医学教育与研究学院开展。79例腰椎滑脱患者同意参与本研究。所有患者均接受保守治疗建议,并按照方案定期随访。招募75名无症状志愿者作为对照组。在79例患者中,54例接受了6个月的随访,在此期间,46例病情改善,8例无改善,25例失访。矢状面脊柱骨盆参数由一名观察者使用Surgimap脊柱软件版本2.1.2(美国纽约州内马里斯公司)进行测量。测量的参数包括PI、骨盆倾斜度(PT)、骶骨倾斜度(SS)、胸椎后凸和腰椎前凸。采用适当的统计方法对患者和对照组的结果进行比较。
正常组和腰椎滑脱组在PI、SS和PT方面存在显著差异(<0.001)。高、低度腰椎滑脱患者之间或病情改善与病情恶化患者之间,所测量的脊柱骨盆参数无显著差异。
PI是所有脊柱骨盆参数中最重要的,它导致腰椎滑脱,但不影响其病情进展。