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当代胚胎植入前遗传学筛查和诊断对非整倍体和遗传性疾病检测的影响。

The impact of contemporary preimplantation genetic screening and diagnosis on the detection of aneuploidy and inherited genetic diseases.

机构信息

Reproductive Medicine Associates of New Jersey, 140 Allen Road, Basking Ridge, New Jersey, 07920.

出版信息

Birth Defects Res. 2018 May 1;110(8):644-647. doi: 10.1002/bdr2.1220.

Abstract

Pre-implantation genetic screening and diagnosis represent important tools for embryo selection in patients undergoing in vitro fertilization. Methods have evolved in recent years and it can be challenging to remain up to date on the current technology. This review article seeks to provide an overview of pre-implantation genetic screening and diagnosis methods, the associated clinical outcomes, and the limitations of this technology.

摘要

胚胎植入前遗传学筛查和诊断是体外受精患者胚胎选择的重要工具。近年来,相关方法不断发展,要跟上当前技术的最新进展颇具挑战。本文旨在概述胚胎植入前遗传学筛查和诊断方法、相关临床结局以及该技术的局限性。

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