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排斥性肾病患者肾移植动脉狭窄的经皮腔内血管成形术

Percutaneous transluminal angioplasty of renal transplant artery stenosis in patients with rejection nephropathy.

作者信息

Stríbrná J, Zabka J, Belán A, Borůvka V, Kocandrle V, Kovác J, Zástava V, Karasová L, Janata V

机构信息

Institute for Clinical and Experimental Medicine, Transplantation Research Programme, Prague, Czechoslovakia.

出版信息

Nephrol Dial Transplant. 1988;3(3):312-6.

PMID:2971900
Abstract

A total of 13 procedures of percutaneous transluminal angioplasty were performed in 11 kidney graft recipients with renal transplant artery stenosis. Nine procedures were technically successful in eight patients (one redilatation was necessary because of restenosis). Graft biopsy confirmed rejection nephropathy in all cases. The outcome could not be evaluated in one patient who died of a concomitant disease shortly after angioplasty. The remaining seven patients (eight percutaneous transluminal angioplasties) showed improvement in hypertension in 63% and in glomerular filtration rate in 50% of procedures, persisting for 6-13 months. A single major complication encountered was a loss of graft related to unsuccessful percutaneous transluminal angioplasty. The results suggest that percutaneous transluminal angioplasty may bring prolonged increase in effective renal plasma flow and glomerular filtration rate even in patients experiencing rejection nephropathy.

摘要

对11例肾移植动脉狭窄的肾移植受者共进行了13次经皮腔内血管成形术。9次手术在8例患者中技术成功(1例因再狭窄需要再次扩张)。移植肾活检在所有病例中均证实为排斥性肾病。1例患者在血管成形术后不久死于伴发疾病,其结局无法评估。其余7例患者(8次经皮腔内血管成形术)中,63%的手术高血压得到改善,50%的手术肾小球滤过率得到改善,持续6至13个月。遇到的唯一严重并发症是与经皮腔内血管成形术失败相关的移植肾丢失。结果表明,即使在患有排斥性肾病的患者中,经皮腔内血管成形术也可能使有效肾血浆流量和肾小球滤过率长期增加。

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