Pérez-San-Gregorio María Á, Martín-Rodríguez Agustín, Sánchez-Martín Milagrosa, Borda-Mas Mercedes, Avargues-Navarro María L, Gómez-Bravo Miguel Á, Conrad Rupert
Department of Personality, Assessment, and Psychological Treatment, University of Seville, Seville, Spain.
Department of Psychology, Universidad Loyola Andalucía, Seville, Spain.
Front Psychiatry. 2018 Apr 18;9:148. doi: 10.3389/fpsyt.2018.00148. eCollection 2018.
The valid assessment of the impact of transplantation on psychological well-being is highly relevant to optimize treatment. However, to date there is no standardized instrument available in Spain. The Transplant Effects Questionnaire (TxEQ) evaluates the specific problems associated with organ transplantation, such as worry about transplant, guilt regarding the donor, disclosure of having undergone transplantation, adherence to medical treatment and responsibility toward the donor, family, friends, or medical staff. Against this backdrop the English original version of the TxEQ was translated into Spanish and validated in a sample of 240 liver transplant recipients. Participants also filled in the Posttraumatic Growth Inventory (PTGI), and the 12-Item Short Form Health Survey (SF-12v.2). Confirmatory factor analysis of the TxEQ-Spanish revealed a five-factor structure equivalent to the English original version, and satisfactory internal consistency (Cronbach's alpha: worry α = 0.82, guilt α = 0.77, disclosure α = 0.91, adherence α = 0.82, responsibility α = 0.83). Results showed that better mental quality of life was associated with higher adherence and disclosure, as well as less worry and guilt. Higher posttraumatic growth was significantly associated with worry, guilt, and responsibility. Interestingly, the most powerful predictor of posttraumatic growth was worry. Analysis of variance showed an interaction effect of PTG and mental quality of life on adherence, with medium PTG being associated with significantly stronger adherence in participants with better mental quality of life. In conclusion our study could successfully adapt and validate the Spanish version of the TxEQ in a large sample of liver transplant recipients. Our findings show a complex relationship between emotional reactions to transplantation, mental quality of life, and posttraumatic growth, which give further insight into inner processes supporting psychological well-being and adherence after liver transplantation.
对移植对心理健康影响的有效评估对于优化治疗至关重要。然而，迄今为止西班牙尚无标准化的评估工具。移植效应问卷（TxEQ）评估与器官移植相关的具体问题，例如对移植的担忧、对供体的愧疚、移植经历的披露、对治疗的依从性以及对供体、家人、朋友或医护人员的责任。在此背景下，TxEQ的英文原版被翻译成西班牙语，并在240名肝移植受者样本中进行了验证。参与者还填写了创伤后成长量表（PTGI）和12项简短健康调查问卷（SF - 12v.2）。对西班牙语版TxEQ的验证性因素分析显示其五因素结构与英文原版等效，且具有令人满意的内部一致性（克朗巴哈系数：担忧α = 0.82，愧疚α = 0.77，披露α = 0.91，依从性α = 0.82，责任α = 0.83）。结果表明，更好的心理生活质量与更高的依从性和披露程度相关，同时担忧和愧疚程度较低。更高的创伤后成长与担忧、愧疚和责任显著相关。有趣的是，创伤后成长最有力的预测因素是担忧。方差分析显示PTG和心理生活质量对依从性有交互作用，中等程度的PTG与心理生活质量较好的参与者中显著更强的依从性相关。总之，我们的研究成功地在大量肝移植受者样本中改编并验证了西班牙语版的TxEQ。我们的研究结果显示了对移植的情绪反应、心理生活质量和创伤后成长之间的复杂关系，这进一步深入了解了支持肝移植后心理健康和依从性的内在过程。
