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长效促黄体生成素释放激素类似物(诺雷德)对前列腺癌的影响:经直肠超声评估

Effect of long-acting LHRH analog (Zoladex) on prostate cancer: evaluated by transrectal ultrasonography.

作者信息

Drago J R, Nesbitt J A, Cirulli C

机构信息

Department of Surgery, Ohio State University, Columbus.

出版信息

Urology. 1988 Oct;32(4):285-7. doi: 10.1016/0090-4295(88)90227-0.

DOI:10.1016/0090-4295(88)90227-0
PMID:2972104
Abstract

Transrectal ultrasonography has proved valuable in assessing the effect of primary treatment modalities for prostate carcinoma. This study shows patients who had a significant reduction in primary tumor volume had a significantly better prognosis and had less local symptoms than did the group of patients that did not have a significant reduction (less than 50%) in primary volume secondary to therapy. Patients were treated with either castration or Zoladex and all had Stage D2 cancer of the prostate.

摘要

经直肠超声检查已被证明在评估前列腺癌主要治疗方式的效果方面具有重要价值。本研究表明,与那些因治疗后原发肿瘤体积没有显著缩小(缩小不到50%)的患者组相比,原发肿瘤体积显著缩小的患者预后明显更好,局部症状也更少。患者接受了去势治疗或使用戈舍瑞林,所有患者均患有D2期前列腺癌。

相似文献

1
Effect of long-acting LHRH analog (Zoladex) on prostate cancer: evaluated by transrectal ultrasonography.长效促黄体生成素释放激素类似物(诺雷德)对前列腺癌的影响:经直肠超声评估
Urology. 1988 Oct;32(4):285-7. doi: 10.1016/0090-4295(88)90227-0.
2
Renewal timing of long-acting depot luteinizing hormone-releasing hormone agonist (Zoladex) is critical in the treatment of hormone-dependent rat prostatic carcinoma (R3327-H).
Prostate. 1987;11(3):281-90. doi: 10.1002/pros.2990110308.
3
[Chemical castration using a depot LHRH-agonist as a palliative therapy concept in prostatic carcinoma--clinical, endocrinological and experimental studies].[使用长效促黄体生成素释放激素激动剂进行化学去势作为前列腺癌姑息治疗概念的临床、内分泌及实验研究]
Wien Klin Wochenschr. 1990 Nov 9;102(21):640-7.
4
[Treatment of carcinoma of the prostate with analogs of LHRH].
Rev Clin Esp. 1986 Nov;179(8):407-11.
5
Zoladex: a sustained-release, monthly luteinizing hormone-releasing hormone analogue for the treatment of advanced prostate cancer.诺雷德:一种用于治疗晚期前列腺癌的长效、每月一次的促黄体生成素释放激素类似物。
J Clin Oncol. 1987 Jun;5(6):912-7. doi: 10.1200/JCO.1987.5.6.912.
6
Treatment of metastatic prostate carcinoma with the depot LRH analog Zoladex.用长效促性腺激素释放激素类似物戈舍瑞林治疗转移性前列腺癌。
Prostate. 1988;12(2):119-27. doi: 10.1002/pros.2990120203.
7
Long-term therapy with a depot luteinizing hormone-releasing hormone analogue (Zoladex) in patients with advanced prostatic carcinoma.长效促黄体生成素释放激素类似物(诺雷德)用于晚期前列腺癌患者的长期治疗。
J Urol. 1988 Oct;140(4):775-7. doi: 10.1016/s0022-5347(17)41809-x.
8
Kinetic evaluation of the effect of LHRH analog on prostatic cancer using transrectal ultrasonotomography.
Prostate. 1987;10(1):11-7. doi: 10.1002/pros.2990100104.
9
[Zoladex in prostatic carcinoma].
Drugs Exp Clin Res. 1990;16 Suppl:19-29.
10
[LHRH analogs--new possibilities in the treatment of prostatic cancer].
Pol Tyg Lek. 1984;39(29-30):1009-12.