长效促黄体生成素释放激素类似物（诺雷德）对前列腺癌的影响：经直肠超声评估
Effect of long-acting LHRH analog (Zoladex) on prostate cancer: evaluated by transrectal ultrasonography.
作者信息
Drago J R, Nesbitt J A, Cirulli C
机构信息
Department of Surgery, Ohio State University, Columbus.
出版信息
Urology. 1988 Oct;32(4):285-7. doi: 10.1016/0090-4295(88)90227-0.
Transrectal ultrasonography has proved valuable in assessing the effect of primary treatment modalities for prostate carcinoma. This study shows patients who had a significant reduction in primary tumor volume had a significantly better prognosis and had less local symptoms than did the group of patients that did not have a significant reduction (less than 50%) in primary volume secondary to therapy. Patients were treated with either castration or Zoladex and all had Stage D2 cancer of the prostate.
经直肠超声检查已被证明在评估前列腺癌主要治疗方式的效果方面具有重要价值。本研究表明，与那些因治疗后原发肿瘤体积没有显著缩小（缩小不到50%）的患者组相比，原发肿瘤体积显著缩小的患者预后明显更好，局部症状也更少。患者接受了去势治疗或使用戈舍瑞林，所有患者均患有D2期前列腺癌。
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