11种抗人白细胞单克隆抗体与几种家畜淋巴细胞的反应性。
Reactivity of eleven anti-human leucocyte monoclonal antibodies with lymphocytes from several domestic animals.
作者信息
Aasted B, Blixenkrone-Møller M, Larsen E B, Bielefeldt Ohmann H, Simesen R B, Uttenthal A
机构信息
Royal Veterinary and Agricultural University of Copenhagen, Department of Veterinary Virology and Immunology, Frederiksberg C, Denmark.
出版信息
Vet Immunol Immunopathol. 1988 Jul;19(1):31-8. doi: 10.1016/0165-2427(88)90044-x.
Nine commercially available monoclonal antibodies and two monoclonal antibodies from The American Type Culture Collection, raised against various human leucocyte surface antigens, were tested on lymphocytes from cow, sheep, goat, swine, horse, cat, dog, mink, and rabbit as well as man. Four antibodies bound to lymphocytes from some of the animals. These were the antibodies against CD8 and CD4 antigen, the antibody to C3b-receptor, and the antibody to the HLA-DR antigen. The CD8 antigen-reactive antibody reacted with lymphocytes from mink, cat, dog, and sheep, while the CD4 antigen-reactive antibody reacted with lymphocytes from mink. The anti-C3b-R antibody reacted with lymphocytes from horse, swine, dog, and cat, and the anti-HLA-DR reacted with lymphocytes from cow, goat, sheep, horse, dog, cat, and mink.
对九种市售单克隆抗体以及来自美国模式培养物集存库的两种针对各种人类白细胞表面抗原产生的单克隆抗体，在牛、羊、山羊、猪、马、猫、狗、水貂和兔子以及人类的淋巴细胞上进行了测试。四种抗体与一些动物的淋巴细胞结合。它们是抗CD8和CD4抗原的抗体、抗C3b受体抗体以及抗HLA-DR抗原抗体。抗CD8抗原反应性抗体与水貂、猫、狗和绵羊的淋巴细胞发生反应，而抗CD4抗原反应性抗体与水貂的淋巴细胞发生反应。抗C3b-R抗体与马、猪、狗和猫的淋巴细胞发生反应，抗HLA-DR抗体与牛、山羊、绵羊、马、狗、猫和水貂的淋巴细胞发生反应。
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