Kreuzer Michaela, Sames-Dolzer Eva, Schausberger Laura, Tulzer Andreas, Ratschiller Thomas, Haizinger Bettina, Tulzer Gerald, Mair Rudolf
Division of Paediatric Cardiac Surgery, Children's Heart Centre Linz, Linz, Austria.
Division of Paediatric Cardiology, Children's Heart Centre Linz, Linz, Austria.
Interact Cardiovasc Thorac Surg. 2018 Nov 1;27(5):742-748. doi: 10.1093/icvts/ivy147.
Double-arterial cannulation enables cerebral perfusion and lower body perfusion during aortic arch reconstruction. The aim of this study was to analyse and report our experience of using this cannulation and perfusion technique on paediatric patients.
A retrospective single-centre study was carried out on 407 consecutive paediatric patients who underwent an aortic arch reconstruction under double-arterial cannulation between 2003 and 2015. The median age of the patients at surgery was 8 (range 2-5570) days, and body weight was 3.3 (range 1.8-60) kg. All operations were performed through standard median sternotomy. One arterial cannula was inserted into the innominate artery and the second one into the supradiaphragmatic descending aorta. Primary end points were 30-day mortality, acute renal failure requiring dialysis and time until lactate level decreased to ≤2 mmol/l postoperatively.
We found an in-hospital mortality of 8.6%. Lethal incident was not associated with the cannulation method, and 1 intraoperative lesion of the descending aorta could be repaired immediately. The median lactate level of the patients on arrival at the intensive care unit was 3.5 mmol/l [quartile (Q)1: 2.3-Q3: 4.7] and creatinine was 0.48 mg/100 ml (Q1: 0.40-Q3: 0.58). The longest duration until the lactate level decreased to ≤ 2 mmol/l was found in the group of 264 univentricular patients (median 11 h, Q1: 6-Q3: 24). Seven (1.7%) patients of the whole cohort required peritoneal dialysis postoperatively.
Double-arterial cannulation is a simple and safe method for perfusing the brain and the lower parts of the body during aortic arch reconstruction. Perioperative survival and freedom from procedure-related complications in this demanding patient population are encouraging.
双动脉插管可在主动脉弓重建期间实现脑灌注和下半身灌注。本研究的目的是分析并报告我们在儿科患者中使用这种插管和灌注技术的经验。
对2003年至2015年间连续接受双动脉插管下主动脉弓重建的407例儿科患者进行了一项回顾性单中心研究。患者手术时的中位年龄为8(范围2 - 5570)天,体重为3.3(范围1.8 - 60)千克。所有手术均通过标准正中胸骨切开术进行。一根动脉插管插入无名动脉,另一根插入膈上降主动脉。主要终点为30天死亡率、需要透析的急性肾衰竭以及术后乳酸水平降至≤2 mmol/L所需的时间。
我们发现院内死亡率为8.6%。致命事件与插管方法无关,1例降主动脉术中损伤得以立即修复。患者入住重症监护病房时的中位乳酸水平为3.5 mmol/L [四分位数(Q)1:2.3 - Q3:4.7],肌酐为0.48 mg/100 ml(Q1:0.40 - Q3:0.58)。在264例单心室患者组中,乳酸水平降至≤2 mmol/L所需的最长时间为(中位时间11小时,Q1:6 - Q3:24)。整个队列中有7例(1.7%)患者术后需要腹膜透析。
双动脉插管是主动脉弓重建期间灌注脑和身体下部的一种简单且安全的方法。在这群要求苛刻的患者中,围手术期生存率及无手术相关并发症令人鼓舞。