Department of Pediatric Cardiac Surgery, E. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation.
Interact Cardiovasc Thorac Surg. 2022 Jul 9;35(2). doi: 10.1093/icvts/ivac186.
The appropriate approach for surgical repair of coarctation of the aorta with a ventricular septal defect (VSD) remains controversial. This study evaluated the outcomes of primary repair of VSDs with periventricular device closure without cardiopulmonary bypass through a left thoracotomy in patients without arch hypoplasia.
We selected 21 patients aged <1 year, including 7 neonates, who underwent repair of coarctation of the aorta with periventricular device closure of a VSD.
The median occluder size was 6 (range, 5-8) mm. The median mechanical ventilation time was 14 (range, 2-68) h, and the median duration of hospital stay was 11 (range, 7-16) days. No reoperations were required to correct VSD shunting, and the median residual shunt size was 1 (range, 1-2) mm. The median follow-up period was 13 (range, 4-31) months. No late deaths were reported, and no haemodynamically significant pressure gradient at the anastomotic site was observed. The median distal aortic arch z-score was 0.39 (range, -0.1-to 0.9). Only 1 patient had a permanent pacemaker implanted towards the end of the follow-up period.
Periventricular device closure can be used safely for closure of VSD in children with coarctation of the aorta without a hypoplastic aortic arch, even in neonates, to reduce the risk of prolonged cardiopulmonary bypass. This hybrid approach can be performed with a low incidence of rhythm disturbances and residual shunting. However, a meticulous assessment of the VSD anatomy is essential to avoid any unfavourable events.
合并室间隔缺损(VSD)的主动脉缩窄的手术修复方法仍存在争议。本研究评估了通过左开胸不使用体外循环,经心外膜装置对无弓降部发育不良的患者行 VSD 直接修补的结果。
我们选择了 21 名年龄<1 岁的患者,包括 7 名新生儿,他们均通过经心外膜装置对 VSD 行主动脉缩窄修补。
中位封堵器大小为 6(范围:5-8)mm。中位机械通气时间为 14(范围:2-68)h,中位住院时间为 11(范围:7-16)d。无再次手术纠正 VSD 分流,中位残余分流大小为 1(范围:1-2)mm。中位随访时间为 13(范围:4-31)个月。无晚期死亡病例,吻合口无血流动力学意义的压力梯度。中位远端主动脉弓 Z 值为 0.39(范围:-0.1-0.9)。仅 1 例患者在随访期末植入了永久性起搏器。
对于无弓降部发育不良的主动脉缩窄合并 VSD 的患儿,即使是新生儿,经心外膜装置闭合 VSD 可安全使用,以降低体外循环时间延长的风险。这种杂交方法可使节律紊乱和残余分流的发生率较低。然而,仔细评估 VSD 解剖结构对于避免任何不良事件至关重要。