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一期非体外循环下心室间隔缺损合并主动脉缩窄矫治术治疗小儿先天性心脏病

Single-stage off-pump repair of coarctation of the aorta and ventricular septal defects in children.

机构信息

Department of Pediatric Cardiac Surgery, E. Meshalkin National Medical Research Center, Novosibirsk, Russian Federation.

出版信息

Interact Cardiovasc Thorac Surg. 2022 Jul 9;35(2). doi: 10.1093/icvts/ivac186.

Abstract

OBJECTIVES

The appropriate approach for surgical repair of coarctation of the aorta with a ventricular septal defect (VSD) remains controversial. This study evaluated the outcomes of primary repair of VSDs with periventricular device closure without cardiopulmonary bypass through a left thoracotomy in patients without arch hypoplasia.

METHODS

We selected 21 patients aged <1 year, including 7 neonates, who underwent repair of coarctation of the aorta with periventricular device closure of a VSD.

RESULTS

The median occluder size was 6 (range, 5-8) mm. The median mechanical ventilation time was 14 (range, 2-68) h, and the median duration of hospital stay was 11 (range, 7-16) days. No reoperations were required to correct VSD shunting, and the median residual shunt size was 1 (range, 1-2) mm. The median follow-up period was 13 (range, 4-31) months. No late deaths were reported, and no haemodynamically significant pressure gradient at the anastomotic site was observed. The median distal aortic arch z-score was 0.39 (range, -0.1-to 0.9). Only 1 patient had a permanent pacemaker implanted towards the end of the follow-up period.

CONCLUSIONS

Periventricular device closure can be used safely for closure of VSD in children with coarctation of the aorta without a hypoplastic aortic arch, even in neonates, to reduce the risk of prolonged cardiopulmonary bypass. This hybrid approach can be performed with a low incidence of rhythm disturbances and residual shunting. However, a meticulous assessment of the VSD anatomy is essential to avoid any unfavourable events.

摘要

目的

合并室间隔缺损(VSD)的主动脉缩窄的手术修复方法仍存在争议。本研究评估了通过左开胸不使用体外循环,经心外膜装置对无弓降部发育不良的患者行 VSD 直接修补的结果。

方法

我们选择了 21 名年龄<1 岁的患者,包括 7 名新生儿,他们均通过经心外膜装置对 VSD 行主动脉缩窄修补。

结果

中位封堵器大小为 6(范围:5-8)mm。中位机械通气时间为 14(范围:2-68)h,中位住院时间为 11(范围:7-16)d。无再次手术纠正 VSD 分流,中位残余分流大小为 1(范围:1-2)mm。中位随访时间为 13(范围:4-31)个月。无晚期死亡病例,吻合口无血流动力学意义的压力梯度。中位远端主动脉弓 Z 值为 0.39(范围:-0.1-0.9)。仅 1 例患者在随访期末植入了永久性起搏器。

结论

对于无弓降部发育不良的主动脉缩窄合并 VSD 的患儿,即使是新生儿,经心外膜装置闭合 VSD 可安全使用,以降低体外循环时间延长的风险。这种杂交方法可使节律紊乱和残余分流的发生率较低。然而,仔细评估 VSD 解剖结构对于避免任何不良事件至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8134/9291394/8ef3af121434/ivac186f4.jpg

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