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[银杏萜内酯的研究进展]

[Research development of ginkgo terpene lactones].

作者信息

Geng Ting, Shen Wen-Wen, Wang Jia-Jia, Huang Wen-Zhe, Wang Zhen-Zhong, Xiao Wei

机构信息

Jiangsu Kanion Parmaceutical Co., Ltd., Lianyungang 222001, China.

State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(7):1384-1391. doi: 10.19540/j.cnki.cjcmm.20180312.001.

DOI:10.19540/j.cnki.cjcmm.20180312.001
PMID:29728027
Abstract

Ginkgo terpene lactones, as an important active ingredient from Ginkgo leaves, has high medicinal values and has been widely used in clinics. This article would review the researches both at home and abroad, including chemical composition, structure-activity relationship, analytical methods, pharmacological effects, pharmacokinetic characteristics, and so on, providing a reference for further development and utilization of ginkgo terpene lactones.

摘要

银杏萜内酯作为银杏叶中的一种重要活性成分,具有很高的药用价值,已在临床上广泛应用。本文将综述国内外的相关研究,包括化学成分、构效关系、分析方法、药理作用、药代动力学特征等,为银杏萜内酯的进一步开发利用提供参考。

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1
[Research development of ginkgo terpene lactones].[银杏萜内酯的研究进展]
Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(7):1384-1391. doi: 10.19540/j.cnki.cjcmm.20180312.001.
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The efficacy and safety of ginkgo terpene lactone preparations combined with antiplatelet aents in the treatment of ischemic stroke: a systematic review and meta-analysis.银杏萜内酯制剂联合抗血小板药物治疗缺血性脑卒中的疗效和安全性:一项系统评价与Meta分析
Front Pharmacol. 2025 Mar 19;16:1554207. doi: 10.3389/fphar.2025.1554207. eCollection 2025.
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Effectiveness of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke.银杏二萜内酯葡胺对急性缺血性脑卒中患者认知功能的有效性
Open Med (Wars). 2024 Mar 13;19(1):20240908. doi: 10.1515/med-2024-0908. eCollection 2024.
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The Efficacy and Safety of Ginkgo Terpene Lactone Preparations in the Treatment of Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
银杏萜内酯制剂治疗缺血性脑卒中的疗效与安全性:一项随机临床试验的系统评价与Meta分析
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Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.葡萄糖酸内酯通过激活蛋白激酶Cε/细胞外信号调节激酶信号通路减轻心肌缺血/再灌注损伤及心律失常。
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