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肾盂肉瘤样癌累及输尿管及肾实质并伴有异源性骨肉瘤分化：一例报告并文献复习

Sarcomatoid Carcinoma of Renal Pelvis Involving Ureter and Renal Parenchyma with Heterologous Osteosarcomatous Differentiation: A Case Report and Review of Literature.

作者信息

Mohan Bhavya P, Jayalakshmy P L, Letha V, Bhat Suresh

机构信息

Dept. of Pathology, Government Medical College, Kottayam, Kerala, India.

Dept. of Genitourinary Surgery, Government Medical College, Kottayam, Kerala, India.

出版信息

Iran J Pathol. 2018 Winter;13(1):89-93.

PMID:29731801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5929394/
Abstract

Sarcomatoid carcinoma is a highgrade rare malignant tumor with both epithelial and mesenchymal components. Sarcomatoid carcinoma in the upper urinary tract is very rare. We reported here a case of sarcomatoid carcinoma of renal pelvis with osteosarcomatous differentiation, with involvement of the ureter and renal parenchyma in a 68-year-old female. Histologically, predominant pleomorphic spindle cell sarcoma component with osteoid production and urothelial carcinoma component with in situ areas were identified. Immunohistochemical analysis showed vimentin positivity in sarcomatous component and cytokeratin positivity in carcinomatous component.

摘要

肉瘤样癌是一种具有上皮和间充质成分的高级别罕见恶性肿瘤。上尿路肉瘤样癌非常罕见。我们在此报告一例68岁女性肾盂肉瘤样癌伴骨肉瘤分化，累及输尿管和肾实质。组织学上，可见以产生骨样组织为主的多形性梭形细胞肉瘤成分和原位区域的尿路上皮癌成分。免疫组化分析显示肉瘤成分中波形蛋白阳性，癌成分中细胞角蛋白阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/09a8ecb13fbb/ijp-13-089-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/dafdebc5fc3e/ijp-13-089-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/5edf4e58fb37/ijp-13-089-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/09a8ecb13fbb/ijp-13-089-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/dafdebc5fc3e/ijp-13-089-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/fd2138d93bd0/ijp-13-089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/f6f4955c8dff/ijp-13-089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/e522a730d5b7/ijp-13-089-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/5edf4e58fb37/ijp-13-089-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/7d7e1379b10a/ijp-13-089-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a94/5929394/09a8ecb13fbb/ijp-13-089-g007.jpg

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A case report of a urothelial carcinoma arising in the renal pelvis with exuberant chondrosarcomatous element associated with adrenal metastasis.一例肾盂尿路上皮癌合并肾上腺转移且伴有丰富软骨肉瘤成分的病例报告。
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Sarcomatoid carcinoma of the renal pelvis: Experience of multiple cases over a ten-year period.
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Case report: Sarcomatoid urothelial carcinoma of the renal pelvis masquerading as a renal abscess.病例报告：肾盂肉瘤样尿路上皮癌伪装成肾脓肿。
Front Oncol. 2023 Jan 23;13:1055229. doi: 10.3389/fonc.2023.1055229. eCollection 2023.
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Oncol Lett. 2013 Aug;6(2):513-516. doi: 10.3892/ol.2013.1396. Epub 2013 Jun 13.
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Use of PAX8 and GATA3 in diagnosing sarcomatoid renal cell carcinoma and sarcomatoid urothelial carcinoma.应用 PAX8 和 GATA3 诊断梭形细胞肾细胞癌和梭形细胞尿路上皮癌。
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