Jeunemaitre X, Raynaud A, Pagny J Y, Chatellier G, Julien J, Plouin P F, Lagneau P, Corvol P
Service d'hypertension artérielle, Hôpital Broussais, Paris.
Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:217-20.
From 1985 to 1986, 71 patients with renovascular hypertension were treated by percutaneous transluminal angioplasty (PTA). Among them, 13 (mean age 67 +/- 7 years) had a hypertension refractory to drug therapy (blood pressure: 194 +/- 33/103 +/- 15 mmHg) associated with an impaired renal function (creatinine clearance: 33 +/- 20 ml/mn). Ten had a stenosis in a solitary functioning kidney and a contralateral renal artery thrombosis. Three had bilateral renovascular stenosis. All patients had severe diffuse atherosclerotic disease, i.e. coronary heart disease (n = 7), carotid artery stenosis (n = 6), abdominal aortic aneurysm (n = 3) or arteritis (n = 5). Among these 13 patients, PTA could not be performed in one patient (failure to catheterize the stenosis) and two immediate renal artery dissections were observed: the first was accompanied by a thrombosis of the renal artery which could be successfully treated in emergency by surgical revascularization. The second occurred in a segmental renal branch and did not require surgery since it did not induced further impairment of renal function. Among the 10 remaining patients, nine PAT were classified as immediate angiographic success. One incomplete result required a second PTA 6 months later. Three important inguinal hematomas were observed and blood transfusion was required in 2. Seven patients have been reevaluated after a follow-up of 3 to 22 months. Restenosis occurred in two patients, 6 and 20 months respectively after PTA. A successful surgical revascularization was performed in these 2 patients.(ABSTRACT TRUNCATED AT 250 WORDS)
1985年至1986年,71例肾血管性高血压患者接受了经皮腔内血管成形术(PTA)治疗。其中,13例(平均年龄67±7岁)患者药物治疗难治性高血压(血压:194±33/103±15 mmHg),伴有肾功能受损(肌酐清除率:33±20 ml/min)。10例患者单功能肾存在狭窄且对侧肾动脉血栓形成。3例患者双侧肾血管狭窄。所有患者均患有严重弥漫性动脉粥样硬化疾病,即冠心病(n = 7)、颈动脉狭窄(n = 6)、腹主动脉瘤(n = 3)或动脉炎(n = 5)。在这13例患者中,1例患者无法进行PTA(未能成功插入导管至狭窄处),观察到2例即刻肾动脉夹层:第一例伴有肾动脉血栓形成,可通过紧急手术血管重建成功治疗。第二例发生在肾段分支,由于未导致肾功能进一步损害,无需手术。在其余10例患者中,9例PTA被分类为即刻血管造影成功。1例不完全成功的结果在6个月后需要进行第二次PTA。观察到3例严重腹股沟血肿,2例需要输血。7例患者在随访3至22个月后接受了重新评估。2例患者分别在PTA后6个月和20个月出现再狭窄。这2例患者均成功进行了手术血管重建。(摘要截断于250字)