活体供肝肝移植：技术创新。

Living Donor Liver Transplantation: Technical Innovations.

机构信息

Department of Surgery, University of Illinois at Chicago, 840 South Wood Street, CSB 401, MC 958, Chicago, IL 60612, USA.

Department of Surgery, Tulane University, 1415 Tulane Avenue, #HC-5, New Orleans, LA 70112-2632, USA.

出版信息

Gastroenterol Clin North Am. 2018 Jun;47(2):253-265. doi: 10.1016/j.gtc.2018.01.001.

DOI:10.1016/j.gtc.2018.01.001

PMID:29735022

Abstract

Living donor liver transplantation (LDLT) has found a place to serve the end-stage liver disease community as the donor safety and recipient suitability has been elucidated. Donor safety is of paramount importance and transplant programs must continue endeavors to maintain the highest possible standards. At the same time, adequacy of grafts based on recipient clinical status via their model for end-stage liver disease (MELD) score and volumetric studies to achieve a GRBWR >0.8, along with special attention to anatomic tailoring and portal venous flow optimization are necessary for successful transplantation. Technical innovations have improved sequentially the utility and availability of LDLT.

摘要

活体肝移植（LDLT）已经找到了为终末期肝病患者服务的位置，因为供体的安全性和受者的适宜性已经得到了阐明。供体的安全性至关重要，移植项目必须继续努力保持尽可能高的标准。与此同时，根据受者的临床状况（通过终末期肝病模型评分和体积研究）获得合适的移植物，以实现 GRBWR>0.8，同时特别注意解剖结构的定制和门静脉血流的优化，这些都是成功移植所必需的。技术创新已经逐步提高了 LDLT 的实用性和可用性。