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活体肝移植中的门体侧支循环:究竟在大惊小怪些什么?

Portosystemic collaterals in living donor liver transplantation: What is all the fuss about?

作者信息

Reddy Mettu Srinivas, Rela Mohamed

机构信息

Institute of Liver Disease and Transplantation, Gleneagles Global Hospital, Chennai, India.

National Foundation for Liver Research, Chennai, India.

出版信息

Liver Transpl. 2017 Apr;23(4):537-544. doi: 10.1002/lt.24719.

DOI:10.1002/lt.24719
PMID:28073180
Abstract

Portosystemic collaterals are a common finding in patients with cirrhosis undergoing liver transplantation. Recently, there has been a renewed interest regarding their significance in the setting of living donor liver transplantation (LDLT) due to concerns of graft hypoperfusion or hyperperfusion and its impact on early posttransplant outcomes. Presence of these collaterals has greater significance in the LDLT setting when compared with the deceased donor liver transplantation setting as dictated by the difference in the physiology of partial liver grafts. We discuss current thinking of portal flow dynamics and the techniques for dealing with this clinical problem. Liver Transplantation 23 537-544 2017 AASLD.

摘要

门体分流支在接受肝移植的肝硬化患者中很常见。最近,由于担心移植物灌注不足或灌注过多及其对移植后早期结局的影响,人们对其在活体肝移植(LDLT)中的意义重新产生了兴趣。与尸体供肝移植相比,由于部分肝移植物生理学差异,这些分流支的存在在LDLT中具有更大的意义。我们讨论了目前关于门静脉血流动力学的观点以及处理这一临床问题的技术。《肝脏移植》2017年第23卷537 - 544页,美国肝病研究学会。

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