Taylor S M, Mallon T R, Green W P, McLoughlin M F, Bryson D G
Veterinary Research Laboratory, Stormont, Belfast.
Vet Rec. 1988 Oct 8;123(15):391-5. doi: 10.1136/vr.123.15.391.
A group of 12 winter-born calves was divided into two groups of six. During the following summer one group grazed on pasture infected with Dictyocaulus viviparus, and was treated with ivermectin injections at three, eight and 13 weeks after turn out. The other group remained housed. Both groups were housed during the winter and then together with a group of younger calves were challenged with a trickle infection of D viviparus larvae at the rate of 25 third stage larvae/kg bodyweight for one month and then slaughtered. The group which had been exposed to previous infection was least affected by parasitic bronchitis and on the basis of serological titres and worm burdens had developed resistance to the challenge infection. The other older group was also more resistant than the younger calves.
一组12头冬季出生的小牛被分成两组,每组6头。在接下来的夏天,一组在感染了胎生网尾线虫的牧场上放牧,并在放牧后第3周、第8周和第13周注射伊维菌素进行治疗。另一组则一直圈养。冬季两组都圈养,然后与一群较年幼的小牛一起,以每公斤体重25条第三期幼虫的剂量进行为期一个月的胎生网尾线虫幼虫连续感染,之后宰杀。之前接触过感染的那组受寄生性支气管炎的影响最小,根据血清学滴度和虫负荷,已对此次攻击感染产生了抵抗力。另一组年龄较大的小牛也比年幼的小牛更具抵抗力。