Armour J, Bairden K, Pirie H M, Ryan W G
Vet Rec. 1987 Jul 4;121(1):5-8. doi: 10.1136/vr.121.1.5.
In May 1985 four groups of 10 calves, aged between four and five months, were turned out on to separate, permanent pastures of equal area which had been seeded during the previous few days with larvae of Dictyocaulus viviparus. One group acted as a control, the second was vaccinated with lungworm vaccine before turnout and treated with thiabendazole three, eight and 13 weeks after turnout, while the third and fourth groups were given ivermectin three times (three, eight and 13 weeks after turnout) and twice (three and eight weeks after turnout), respectively. A severe outbreak of parasitic bronchitis resulted in the death of three control calves within five weeks of turnout and parasitic bronchitis and gastroenteritis affected the second group of calves after approximately four months at pasture. The calves given ivermectin excreted no lungworm larvae and remained free of clinical parasitism throughout the trial.
1985年5月，将四组每组10头、年龄在4至5个月的小牛，分别放到面积相等的永久性牧场上，这些牧场在前几天已接种了胎生网尾线虫幼虫。一组作为对照，第二组在放牧前接种肺线虫疫苗，并在放牧后3周、8周和13周用噻苯达唑进行治疗，而第三组和第四组分别在放牧后3周、8周和13周以及3周和8周三次和两次给予伊维菌素。一次严重的寄生性支气管炎爆发导致3头对照小牛在放牧后5周内死亡，第二组小牛在放牧约4个月后受到寄生性支气管炎和胃肠炎的影响。接受伊维菌素治疗的小牛在整个试验过程中未排出肺线虫幼虫，也未出现临床寄生虫感染。
