曼氏血吸虫亚细胞组分中一种钙刺激、镁依赖的ATP酶活性。
A Ca2+-stimulated, Mg2+-dependent ATPase activity in subcellular fractions from Schistosoma mansoni.
作者信息
Cunha V M, de Souza W, Noël F
机构信息
Departamento de Farmacologia Básica e Clinica, Universidade Federal do Rio de Janeiro, Brazil.
出版信息
FEBS Lett. 1988 Dec 5;241(1-2):65-8. doi: 10.1016/0014-5793(88)81032-9.
PMID:2973994
Abstract
A Ca2+-stimulated, Mg2+-dependent ATPase activity was found in subcellular fractions from Schistosoma mansoni. Its specific and relative activities were higher in the heterogeneous cuticle fraction and in the microsomal fraction. The K0.5 for ATPase activation by free Ca2+ was 0.2-0.5 microM. This is the first description of an ATPase activity stimulated by Ca2+ in the micromolar range in S. mansoni.
摘要
在曼氏血吸虫的亚细胞组分中发现了一种Ca2+刺激、Mg2+依赖的ATP酶活性。其比活性和相对活性在异质角质层组分和微粒体组分中更高。游离Ca2+激活ATP酶的K0.5为0.2 - 0.5微摩尔。这是首次对曼氏血吸虫中微摩尔范围内受Ca2+刺激的ATP酶活性进行描述。
Zotero 插件