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古巴的生殖支原体感染:2014 - 2015年泌尿生殖系统综合征监测

Mycoplasma genitalium infections in Cuba: surveillance of urogenital syndromes, 2014-2015.

作者信息

Mondeja Brian A, Rodríguez Nadia M, Blanco Orestes, Fernández Carmen, Jensen Jørgen S

机构信息

1 Pedro Kourí Tropical Medicine Institute, Center of Research, Diagnosis and Reference in Infectious Diseases, La Habana, Cuba.

2 Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

出版信息

Int J STD AIDS. 2018 Sep;29(10):994-998. doi: 10.1177/0956462418767186. Epub 2018 May 10.

Abstract

Mycoplasma genitalium is an emerging sexually transmitted pathogen implicated in urethritis in men and several inflammatory reproductive tract syndromes in women. The prevalence of M. genitalium infections in Cuban patients with urogenital syndromes is unknown. The aim of this study was to analyse the prevalence of M. genitalium infection in sexually-active Cuban men and women with urogenital syndromes as a part of aetiological surveillance of urogenital syndromes in Cuba. Samples from men and women with urogenital syndromes submitted to the Mycoplasma Reference Laboratory for mycoplasma diagnosis from 1 January 2014 to 1 June 2015 were analysed by polymerase chain reaction (PCR) for detection of M. genitalium. A total of 971 samples were received and processed. Of the patients tested, 5.7% (47/824) of women and 27.9% (41/147) of men were positive for M. genitalium. This paper presents the largest study of M. genitalium infections among Cuban patients with urogenital syndromes and is Cuba's first M. genitalium survey. We suggest that M. genitalium should be considered in the Cuban sexually transmitted infection management protocols as an important pathogen, particularly in men.

摘要

生殖支原体是一种新出现的性传播病原体,与男性尿道炎及女性几种炎症性生殖道综合征有关。古巴泌尿生殖系统综合征患者中生殖支原体感染的患病率尚不清楚。本研究的目的是分析患有泌尿生殖系统综合征的性活跃古巴男女中生殖支原体感染的患病率,作为古巴泌尿生殖系统综合征病因学监测的一部分。对2014年1月1日至2015年6月1日提交给支原体参考实验室进行支原体诊断的患有泌尿生殖系统综合征的男女样本进行聚合酶链反应(PCR)分析,以检测生殖支原体。共接收并处理了971份样本。在接受检测的患者中,女性有5.7%(47/824)、男性有27.9%(41/147)生殖支原体呈阳性。本文介绍了对古巴泌尿生殖系统综合征患者中生殖支原体感染进行的规模最大的研究,也是古巴首次对生殖支原体的调查。我们建议,在古巴性传播感染管理方案中,应将生殖支原体视为一种重要病原体,尤其是在男性中。

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