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频繁跌倒与意识模糊：结节性硬化症患者反复发生低血糖症

Frequent falls and confusion: recurrent hypoglycemia in a patient with tuberous sclerosis complex.

作者信息

Comninos Alexander N, Yang Lisa, Abbara Ali, Dhillo Waljit S, Bassett J H Duncan, Todd Jeannie F

机构信息

Department of Endocrinology Hammersmith Hospital Imperial College Healthcare NHS Trust Du Cane Road London W12 0HS UK.

Section of Endocrinology & Investigative Medicine Department of Medicine Imperial College London Du Cane Road London W12 0HS UK.

出版信息

Clin Case Rep. 2018 Mar 24;6(5):904-909. doi: 10.1002/ccr3.1483. eCollection 2018 May.

DOI:10.1002/ccr3.1483
PMID:29744084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5930219/
Abstract

Recurrent hypoglycemia is common, but its presentation is often insidious resulting in delays in diagnosis and significant morbidity. We describe a case of an insulinoma presenting with falls and confusion in a patient with tuberous sclerosis, demonstrating the importance of early hypoglycemia identification and a potential shared molecular pathogenesis.

摘要

复发性低血糖很常见，但其表现往往隐匿，导致诊断延迟和严重的发病率。我们描述了一例患有结节性硬化症的患者，其胰岛素瘤表现为跌倒和意识模糊，证明了早期识别低血糖的重要性以及潜在的共同分子发病机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/b5f26967a21c/CCR3-6-904-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/4b89063f628b/CCR3-6-904-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/1cd507a4ca58/CCR3-6-904-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/9f9680274ddd/CCR3-6-904-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/0b9e127ef3a7/CCR3-6-904-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/1ea86abe85c6/CCR3-6-904-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/b5f26967a21c/CCR3-6-904-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/4b89063f628b/CCR3-6-904-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/1cd507a4ca58/CCR3-6-904-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/9f9680274ddd/CCR3-6-904-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/0b9e127ef3a7/CCR3-6-904-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/1ea86abe85c6/CCR3-6-904-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b54/5930219/b5f26967a21c/CCR3-6-904-g006.jpg

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本文引用的文献

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ENETS Consensus Guidelines for Standard of Care in Neuroendocrine Tumours: Surgery for Small Intestinal and Pancreatic Neuroendocrine Tumours.神经内分泌肿瘤护理标准的ENETS共识指南：小肠和胰腺神经内分泌肿瘤的手术治疗
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IS THERE A RELATIONSHIP BETWEEN TUBEROUS SCLEROSIS COMPLEX AND INSULINOMA?结节性硬化症复合体与胰岛素瘤之间存在关联吗？
Acta Endocrinol (Buchar). 2022 Jul-Sep;18(3):350-354. doi: 10.4183/aeb.2022.350.
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Diagnostic features of tuberous sclerosis complex: case report and literature review.结节性硬化症复合体的诊断特征：病例报告与文献综述
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血液透析引起的低血糖和血糖紊乱。
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Neuroendocrinology. 2012;95(2):98-119. doi: 10.1159/000335591. Epub 2012 Feb 15.
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