Dalla Barba Gianfranco, Brazzarola Marta, Barbera Claudia, Marangoni Sara, Causin Francesco, Bartolomeo Paolo, Thiebaut de Schotten Michel
INSERM, Paris, France.
Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A), Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Sorbonne Université, Paris, France.
Exp Brain Res. 2018 Jul;236(7):2037-2046. doi: 10.1007/s00221-018-5281-8. Epub 2018 May 9.
Confabulating patients produce statements and actions that are unintentionally incongruous to their history, background, present and future situation. Here we present the very unusual case of a patient with right hemisphere damage and signs of left visual neglect, who, when presented with visual stimuli, confabulated both for consciously undetected and for consciously detected left-sided details. Advanced anatomical investigation suggested a disconnection between the parietal and the temporal lobes in the right hemisphere. A disconnection between the ventral cortical visual stream and the dorsal fronto-parietal networks in the right hemisphere may contribute to confabulatory behaviour by restricting processing of left-sided stimuli to pre-conscious stages in the ventral visual stream.
虚构症患者会产生与他们的病史、背景、当前和未来状况无意相悖的陈述和行为。在此，我们呈现了一个非常特殊的病例，该患者右半球受损并有左侧视觉忽视的症状，当面对视觉刺激时，对于有意识未察觉到的以及有意识察觉到的左侧细节都会虚构。先进的解剖学研究表明右半球顶叶和颞叶之间存在联系中断。右半球腹侧皮质视觉通路与背侧额顶网络之间的联系中断，可能通过将左侧刺激的处理限制在腹侧视觉通路的前意识阶段，从而导致虚构行为。
