Özdemir Nihal, Koç Başak, Arslantaş Esra, Odaman Al Işik, Kelleci Çiğdem, Uysalol Ezgi Pasli, Bayram Cengiz, Ayçiçek Ali
Pediatric Hematology and Oncology Department, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
J Pediatr Hematol Oncol. 2018 Jul;40(5):395. doi: 10.1097/MPH.0000000000001178.
This is the report of a 2-year-old boy who presented with fever, cytopenia, and splenomegaly. The patient was diagnosed with hemophagocytic lymphohistiocytosis (HLH) and treated with HLH-2004 protocol. Repeated bone marrow aspiration showed amastigotes on follow-up. In endemic countries, visceral leishmaniasis should be considered in the differential diagnosis to avoid chemotherapy toxicity.
这是一名2岁男孩的报告，他出现发热、血细胞减少和脾肿大。该患者被诊断为噬血细胞性淋巴组织细胞增生症（HLH），并按照HLH - 2004方案进行治疗。随访时反复骨髓穿刺显示有无鞭毛体。在流行国家，鉴别诊断时应考虑内脏利什曼病，以避免化疗毒性。
