Mohanty N, Chainy G B
Department of Zoology, Utkal University, Vani Vihar, Bhubaneswar/India.
Andrologia. 1988 Sep-Oct;20(5):426-32. doi: 10.1111/j.1439-0272.1988.tb00719.x.
This investigation was undertaken to study the effects of prolactin and bromocriptine on the testis of the musk shrew. None of these treatments had any effect on the weight of testis or on the accessory sex organs. Treatment of prolactin or bromocriptine failed to induce any change in esterified and free cholesterol content of the testis. No significant alterations were also recorded in the levels of macromolecules and in the levels of enzymes of the testis and the prostate gland. On the other hand, bromocriptine treatment resulted in an increase in the activity of Mg2+-ATPase and phospholipid:DNA ratio of the testis with a concomitant decrease in its DNA content. The absence of any change in the content of fructose in the ampullary gland, in the activity of beta-glucuronidase of the kidney, in cholesterol content of the testis, in diameters of seminiferous tubule and Leydig cell nucleus, in activities of acid phosphatase and beta-glucuronidase of the testis and in the weight of accessory sex organs of prolactin and bromocriptine treated musk shrews suggests that prolactin does not play a significant role in regulating the testicular function of the musk shrew.
本研究旨在探讨催乳素和溴隐亭对麝鼩睾丸的影响。这些处理均未对睾丸重量或附属生殖器官产生任何影响。催乳素或溴隐亭处理未能引起睾丸酯化胆固醇和游离胆固醇含量的任何变化。睾丸和前列腺的大分子水平及酶水平也未记录到显著改变。另一方面，溴隐亭处理导致睾丸Mg2+-ATP酶活性和磷脂:DNA比值增加，同时其DNA含量降低。催乳素和溴隐亭处理的麝鼩壶腹腺果糖含量、肾脏β-葡萄糖醛酸酶活性、睾丸胆固醇含量、曲细精管和间质细胞核直径、睾丸酸性磷酸酶和β-葡萄糖醛酸酶活性以及附属生殖器官重量均未发生变化，这表明催乳素在调节麝鼩睾丸功能方面不起重要作用。
