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手辅助活体供肾肾切除术:两种技术的回顾性比较

Hand-assisted living-donor nephrectomy: a retrospective comparison of two techniques.

作者信息

Widmer Jeannette D, Schlegel Andrea, Kron Philipp, Schiesser Marc, Brockmann Jens G, Muller Markus K

机构信息

Department of Surgery, Kantonsspital Frauenfeld, 8500, Frauenfeld, Switzerland.

Division of Visceral and Transplantation Surgery, University Hospital, Zurich, Switzerland.

出版信息

BMC Urol. 2018 May 10;18(1):39. doi: 10.1186/s12894-018-0355-2.

DOI:10.1186/s12894-018-0355-2
PMID:29747596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5946389/
Abstract

BACKGROUND

Living-donor nephrectomy (LDN) is challenging, as surgery is performed on healthy individuals. Minimally invasive techniques for LDN have become standard in most centers. Nevertheless, numerous techniques have been described with no consensus on which is the superior approach. Both hand-assisted retroperitoneoscopic (HARS) and hand-assisted laparoscopic (HALS) LDNs are performed at Zurich University Hospital. The aim of this study was to compare these two surgical techniques in terms of donor outcome and graft function.

METHOD

Retrospective single-center analysis of 60 consecutive LDNs (HARS n = 30; HALS n = 30) from June 2010 to May 2012, including a one-year follow-up of the recipients.

RESULTS

There was no mortality in either group and little difference in the overall complication rates. Median warm ischemia time (WIT) was significantly shorter in the HARS group. The use of laxatives and the incidence of postoperative vomiting were significantly greater in the HALS group. There was no difference between right- and left-sided nephrectomies in terms of donor outcome and graft function.

CONCLUSIONS

Both techniques appear safe for both donors and donated organs. The HARS technique is associated with a shorter WIT and a reduced incidence of postoperative paralytic ileus. Therefore, we consider HARS LDN a valuable alternative to HALS LDN.

摘要

背景

活体供肾肾切除术(LDN)具有挑战性,因为手术是在健康个体身上进行的。在大多数中心,LDN的微创技术已成为标准术式。然而,已有多种技术被描述,但对于哪种方法更优尚无共识。苏黎世大学医院同时开展手辅助后腹腔镜(HARS)和手辅助腹腔镜(HALS)LDN手术。本研究的目的是比较这两种手术技术在供体结局和移植肾功能方面的差异。

方法

对2010年6月至2012年5月期间连续进行的60例LDN手术(HARS组n = 30;HALS组n = 30)进行回顾性单中心分析,包括对受者进行为期一年的随访。

结果

两组均无死亡病例,总体并发症发生率差异不大。HARS组的中位热缺血时间(WIT)明显更短。HALS组使用泻药的情况和术后呕吐发生率明显更高。在供体结局和移植肾功能方面,左右侧肾切除术之间没有差异。

结论

两种技术对供体和捐赠器官似乎都是安全的。HARS技术与较短的WIT和术后麻痹性肠梗阻发生率降低相关。因此,我们认为HARS LDN是HALS LDN的一种有价值的替代方法。

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1
Hand-assisted living-donor nephrectomy: a retrospective comparison of two techniques.手辅助活体供肾肾切除术:两种技术的回顾性比较
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2
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本文引用的文献

1
Renal Perfusion and Function during Pneumoperitoneum: A Systematic Review and Meta-Analysis of Animal Studies.气腹期间的肾脏灌注与功能:动物研究的系统评价和荟萃分析
PLoS One. 2016 Sep 22;11(9):e0163419. doi: 10.1371/journal.pone.0163419. eCollection 2016.
2
Living-Donor Versus Deceased-Donor Kidney Transplantation: Comparison of Psychosocial Consequences for Recipients.活体供体与尸体供体肾移植:受者心理社会后果的比较
Transplant Proc. 2016 Jun;48(5):1498-505. doi: 10.1016/j.transproceed.2016.01.075.
3
Perioperative Complications After Living Kidney Donation: A National Study.活体肾捐献后的围手术期并发症:一项全国性研究。
Am J Transplant. 2016 Jun;16(6):1848-57. doi: 10.1111/ajt.13687. Epub 2016 Mar 10.
4
Long-term outcome of living kidney donation: Position paper of the European Committee on Organ Transplantation (CD-P-TO), Council of Europe.活体肾捐赠的长期结果:欧洲委员会器官移植委员会(CD-P-TO)立场文件
Transpl Int. 2016 Jan;29(1):129-31. doi: 10.1111/tri.12698. Epub 2015 Nov 3.
5
Functional status, time to transplantation, and survival benefit of kidney transplantation among wait-listed candidates.等待名单上的候选者的功能状态、移植时间以及肾移植的生存获益
Am J Kidney Dis. 2015 Nov;66(5):837-45. doi: 10.1053/j.ajkd.2015.05.015. Epub 2015 Jul 7.
6
Right Versus Left Laparoscopic Living-Donor Nephrectomy: A Meta-Analysis.右侧与左侧腹腔镜活体供肾肾切除术:一项Meta分析
Exp Clin Transplant. 2015 Jun;13(3):214-26.
7
A comparison of technique modifications in laparoscopic donor nephrectomy: a systematic review and meta-analysis.腹腔镜供肾切除术技术改良的比较:一项系统评价与荟萃分析
PLoS One. 2015 Mar 27;10(3):e0121131. doi: 10.1371/journal.pone.0121131. eCollection 2015.
8
Comparison of the laparoscopic versus open live donor nephrectomy: an overview of surgical complications and outcome.腹腔镜与开放活体供肾切除术的比较:手术并发症及结果概述
Langenbecks Arch Surg. 2014 Jun;399(5):543-51. doi: 10.1007/s00423-014-1196-4. Epub 2014 Apr 28.
9
Risk of end-stage renal disease following live kidney donation.活体肾捐献后终末期肾病的风险。
JAMA. 2014 Feb 12;311(6):579-86. doi: 10.1001/jama.2013.285141.
10
Can right-sided hand-assisted retroperitoneoscopic donor nephrectomy be advocated above standard laparoscopic donor nephrectomy: a randomized pilot study.右侧手辅助后腹腔镜供肾切除术是否比标准腹腔镜供肾切除术更具优势:一项随机试点研究。
Transpl Int. 2014 Feb;27(2):162-9. doi: 10.1111/tri.12226. Epub 2013 Nov 25.