Department of Materials Science and Engineering, School of Molecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong, 21210, Thailand.
Macromol Rapid Commun. 2018 Jun;39(12):e1800071. doi: 10.1002/marc.201800071. Epub 2018 May 11.
Previous couplings of corrosion inhibitors to redox-responsive polymers via covalent bonding suffer from several drawbacks. It is presented here novel redox-responsive polymer-corrosion inhibitor conjugates that contain self-immolative linkers in their side chains. Very fast redox-induced release of tryptamine, a drug and a corrosion inhibitor, is observed after applying a reductive trigger.
先前通过共价键将缓蚀剂与氧化还原响应性聚合物偶联存在一些缺点。本文提出了新型的氧化还原响应性聚合物-缓蚀剂缀合物,其侧链中含有自毁性连接基团。在施加还原触发后,观察到药物和缓蚀剂色胺的快速氧化还原诱导释放。