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肘部尺神经手术失败后的再次手术效果:系统评价和荟萃分析。

Results of reoperation for failed ulnar nerve surgery at the elbow: a systematic review and meta-analysis.

机构信息

Departments of1Plastic and Reconstructive Surgery.

2Department of Neurology, Donders Institute for Brain, Cognition and Behaviour; and.

出版信息

J Neurosurg. 2019 Mar 1;130(3):686-701. doi: 10.3171/2017.8.JNS17927. Epub 2018 May 11.

Abstract

OBJECTIVE

The clinical results of reoperation for recurrent or persistent ulnar nerve compression at the elbow have not been clearly determined. The aim of this review was to determine overall improvement, residual pain, and sensory and motor deficits following reoperation regardless of the type of primary surgery performed for this condition.

METHODS

In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, a systematic review and meta-analysis of studies was performed. An independent librarian performed a literature search using Ovid MEDLINE, Embase, CINAHL, and the Cochrane Central Register of Controlled Trials (CENTRAL). The Newcastle-Ottawa Scale and the quality appraisal tool described by Moga et al. were used to assess the quality of included case series.

RESULTS

Of the 278 retrieved studies, 16 were eligible for analysis and included a total of 290 patients with failed surgery for ulnar nerve entrapment at the elbow. Relief of symptoms after reoperation was reported in 85% of patients. A decrease in pain was noted in 85% of the patients (95% CI 75%-93%). Only 2.4% of patients with preoperative pain experienced worse pain after reoperation. Motor and sensory function improvement was noted in 77% (95% CI 63%-88%) and 77% (95% CI 61%-90%) of cases, respectively. Complete recovery from signs and symptoms at the final follow-up was noted in 23% of elbows (95% CI 16%-31%).

CONCLUSIONS

Although the level of evidence of the included studies was low, the majority of patients had relief from their complaints after reoperation for recurrent or persistent ulnar nerve compression at the elbow following a previous surgery. The success rate of surgical treatment for a failed surgery was quite remarkable since almost a quarter of the patients completely recovered. Therefore, the authors recommend reoperation as a serious option for patients with this condition.

摘要

目的

肘部尺神经反复或持续性压迫的再手术临床效果尚未明确。本综述旨在确定无论该疾病的初次手术类型如何,患者在接受再手术后整体改善情况、残留疼痛以及感觉和运动功能缺陷。

方法

根据系统评价和荟萃分析的首选报告项目(PRISMA)建议,对研究进行系统回顾和荟萃分析。独立的图书管理员使用 Ovid MEDLINE、Embase、CINAHL 和 Cochrane 对照试验中心注册库(CENTRAL)进行文献检索。使用纽卡斯尔-渥太华量表和 Moga 等人描述的质量评估工具来评估纳入病例系列的质量。

结果

在检索到的 278 项研究中,有 16 项符合分析标准,共纳入 290 例肘部尺神经卡压手术失败的患者。再手术后症状缓解的报告率为 85%。95%置信区间(CI)为 75%-93%,85%的患者疼痛减轻。术前有疼痛的患者中只有 2.4%在再手术后疼痛更严重。77%(95%CI 63%-88%)和 77%(95%CI 61%-90%)的病例分别观察到运动和感觉功能改善。在最终随访时,23%(95%CI 16%-31%)的肘部完全恢复体征和症状。

结论

尽管纳入研究的证据水平较低,但大多数患者在肘部尺神经反复或持续性压迫的初次手术后再次接受手术时,其症状得到缓解。对于手术失败的患者,手术治疗的成功率相当显著,因为近四分之一的患者完全康复。因此,作者建议将再手术作为该疾病患者的一种严重选择。

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