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巴西中西部地区 HIV 垂直传播率高。

High vertical HIV transmission rate in the Midwest region of Brazil.

机构信息

Universidade Federal do Mato Grosso do Sul, Faculdade de Medicina, Campo Grande, MS, Brazil.

Universidade Federal do Mato Grosso do Sul, Hospital Universitário Maria Aparecida Pedrossian, Programa de Residência Multiprofissional em Saúde, Campo Grande, MS, Brazil.

出版信息

Braz J Infect Dis. 2018 May-Jun;22(3):177-185. doi: 10.1016/j.bjid.2018.04.002. Epub 2018 May 9.

Abstract

OBJECTIVES

To estimate vertical HIV transmission rate in a capital city of the Midwest region of Brazil and describe the factors related to transmission.

METHODS

A descriptive epidemiological study based on the analysis of secondary data from the Notifiable Diseases Information System (SINAN). The analysis considered all HIV-infected pregnant women with delivery in Campo Grande-MS in the years 2007-2013 and their HIV-exposed infants.

RESULTS

A total of 218 births of 176 HIV-infected pregnant women were identified during the study period, of which 187 infants were exposed and uninfected, 19 seroconverted, and 12 were still inconclusive in July 2015. Therefore, the overall vertical HIV transmission rate in the period was 8.7%. Most (71.6%) of HIV-infected pregnant women were less than 30 years at delivery, housewives (63.6%) and studied up to primary level (61.9%). Prenatal information was described in 75.3% of the notification forms and approximately 80% of pregnant women received antiretroviral prophylaxis. Among infants, 86.2% received prophylaxis, but little more than half received it during the whole period recommended by the Brazilian Ministry of Health. Among the exposed children, 11.3% were breastfed.

CONCLUSION

The vertical HIV transmission rate has increased over the years and the recommended interventions have not been fully adopted. HIV-infected pregnant women need adequate prophylactic measures in prenatal, intrapartum and postpartum, requiring greater integration among health professionals.

摘要

目的

估计巴西中西部首府的垂直 HIV 传播率,并描述与传播相关的因素。

方法

这是一项基于对巴西中南部城市 Campo Grande 市 2007-2013 年期间可报告疾病信息系统(SINAN)中二次数据进行分析的描述性流行病学研究。该分析考虑了所有在该地区分娩的 HIV 感染孕妇及其 HIV 暴露婴儿。

结果

在研究期间共发现 218 例 176 例 HIV 感染孕妇分娩,其中 187 例婴儿暴露但未感染,19 例发生血清转换,12 例在 2015 年 7 月仍未确诊。因此,该时期垂直 HIV 传播率总体为 8.7%。大多数(71.6%)HIV 感染孕妇分娩时年龄小于 30 岁,以家庭主妇(63.6%)和小学及以下学历(61.9%)为主。75.3%的通报表中描述了产前信息,约 80%的孕妇接受了抗逆转录病毒预防。在婴儿中,86.2%接受了预防,但仅有略多于一半的婴儿在整个推荐的预防时间内接受了预防。在暴露儿童中,11.3%接受了母乳喂养。

结论

垂直 HIV 传播率逐年上升,推荐的干预措施并未得到充分采纳。HIV 感染孕妇在产前、分娩和产后需要采取适当的预防措施,需要卫生专业人员之间更好地整合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acde/9425683/83982457bef1/gr1.jpg

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