Saint Louis University, School of Medicine, St. Louis, MO 63104, USA.
Saint Louis University College of Public Health and Social Justice, Department of Epidemiology, St. Louis, MO 63104, USA.
Vaccine. 2018 Jun 14;36(25):3629-3634. doi: 10.1016/j.vaccine.2018.05.022. Epub 2018 May 9.
There exists a significant gap in vaccine coverage of the human papillomavirus (HPV) among college-aged students. This study assessed sexual risk-taking behavior among university students and analyzed predictors of HPV vaccine initiation and completion in this population.
Data (n = 746) were from an anonymous online, cross-sectional survey distributed to university students, between the ages of 19-26 years, at a private Midwestern university. Both chi-square and multivariable logistics regression models estimated the association between sociodemographic characteristics and sexual risk factors (including number of vaginal sexual partners, number of oral sexual partners, initiation of oral sex, and initiation of vaginal sex), with HPV vaccine initiation and completion.
A significant number of participants (40%) had not received a single dose of the HPV vaccine series. Of those who initiated the series, more than half (51%) did not achieve completion. Additionally, a greater number of participants have had multiple (4 or more) oral sexual partners than vaginal sexual partners (25.7% vs. 20.3%). After adjusting for covariates, it was found that sexual risk factors were not significantly associated with HPV vaccine initiation or completion.
HPV vaccine initiation and completion rates are suboptimal among university students. High levels of sexual-risk taking behaviors associated with HPV infection persist, yet are not significant predictors of HPV vaccine behaviors in this age group. To increase uptake among 18-26-year-old students, future public health interventions should focus on HPV vaccine education and uptake across the entire population, irrespective of sexual risk profile.
在大学生中,人乳头瘤病毒 (HPV) 疫苗的接种率存在显著差距。本研究评估了大学生的性行为风险,并分析了该人群中 HPV 疫苗接种启动和完成的预测因素。
数据(n=746)来自于一项在中西部一所私立大学向 19-26 岁的大学生进行的匿名在线横断面调查。卡方检验和多变量逻辑回归模型分别估计了社会人口统计学特征和性行为风险因素(包括阴道性交伴侣数、口交性伴侣数、口交开始时间和阴道性交开始时间)与 HPV 疫苗接种启动和完成之间的关联。
相当数量的参与者(40%)没有接种过 HPV 疫苗系列的任何一剂。在那些开始接种系列疫苗的人中,超过一半(51%)没有完成全程接种。此外,更多的参与者有多个(4 个及以上)口交性伴侣,而不是阴道性交性伴侣(25.7%比 20.3%)。在调整了协变量后,发现性行为风险因素与 HPV 疫苗接种启动或完成均无显著关联。
大学生 HPV 疫苗接种启动和完成率不理想。与 HPV 感染相关的性行为风险水平较高,但在该年龄组中,并非 HPV 疫苗行为的显著预测因素。为了提高 18-26 岁学生的接种率,未来的公共卫生干预措施应侧重于针对整个人群的 HPV 疫苗教育和接种,而不论其性行为风险状况如何。