Department of General Medicine, Royal Children's Hospital Melbourne, Melbourne, Australia.
Immunisation Service, Royal Children's Hospital Melbourne, Melbourne, Australia.
Vaccine. 2018 Jun 14;36(25):3681-3685. doi: 10.1016/j.vaccine.2018.05.018. Epub 2018 May 9.
Sedation for immunizations is of particular importance in a subset of paediatric patients with anxiety disorders, needle phobia, developmental or behavioural disorders. The Royal Children's Hospital (RCH) Melbourne offers a unique immunization under sedation service for these patients. We aimed to evaluate the number and types of patients using inpatient sedation for immunizations, distraction and sedation techniques used, and outcomes of these procedures.
A medical record review was conducted on all patients who had immunization under sedation between January 2012 to December 2016 in the RCH Day Medical Unit (DMU).
A total of 139 children and adolescents had 213 vaccination encounters. More than half of the vaccination encounters involved multiple vaccines. A total of 400 vaccines were administered. One third of patients (32.3%) had multiple DMU admissions for vaccinations. The median age of patients was 13 years. There were only 10 (4.7%) failed attempts at vaccination; all due to patient non-compliance with prescribed sedation. The majority of patients (58.9%) had a diagnosis of needle phobia. Sedation was most commonly adequately achieved with inhaled nitrous oxide (54.7% sole agent). Midazolam was often used as an adjunct therapy (42.8%). Local anaesthetic cream or play therapy, were used in only 5.9% and 3.9% of patients respectively, although this may reflect poor documentation rather than actual practice.
For a subset of paediatric patients for which standard immunization procedures have failed, distraction techniques and conscious sedation enable immunizations to be given safely and effectively. Future research will develop protocols to streamline immunization procedures under sedation.
在患有焦虑症、恐惧症、发育或行为障碍的儿童亚群中,免疫接种时的镇静尤为重要。墨尔本皇家儿童医院(RCH)为这些患者提供了一种独特的镇静下免疫接种服务。我们旨在评估因免疫接种而接受住院镇静的患者数量和类型、使用的分散注意力和镇静技术,以及这些程序的结果。
对 2012 年 1 月至 2016 年 12 月期间在 RCH 日间医疗部(DMU)接受镇静下免疫接种的所有患者进行病历回顾。
共有 139 名儿童和青少年进行了 213 次疫苗接种。超过一半的疫苗接种涉及多种疫苗。共接种了 400 支疫苗。三分之一的患者(32.3%)因疫苗接种而多次入住 DMU。患者的中位年龄为 13 岁。仅有 10 例(4.7%)疫苗接种尝试失败;均因患者不遵守规定的镇静而导致。大多数患者(58.9%)有恐惧症诊断。最常通过吸入一氧化二氮(54.7%的单一药物)充分实现镇静。咪达唑仑通常作为辅助治疗(42.8%)。局部麻醉乳膏或游戏疗法仅分别在 5.9%和 3.9%的患者中使用,尽管这可能反映了记录不良而不是实际做法。
对于标准免疫接种程序失败的儿童亚群,分散注意力技术和清醒镇静可安全有效地进行免疫接种。未来的研究将制定方案,使镇静下免疫接种程序更加简化。