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测量缅甸注射毒品人群中个人层面的针具和注射器覆盖率。

Measuring individual-level needle and syringe coverage among people who inject drugs in Myanmar.

机构信息

Burnet Institute, 85 Commercial Rd, Melbourne, VIC, 3004, Australia; School of Public Health and Preventive Medicine, Monash University, 99 Commercial Rd, Melbourne, VIC, 3004, Australia.

Burnet Institute Myanmar, Second floor, 226 U Wisara Road, Wizaya Plaza, Bahan Township, Yangon, Myanmar.

出版信息

Int J Drug Policy. 2018 Aug;58:22-30. doi: 10.1016/j.drugpo.2018.04.010. Epub 2018 May 11.

Abstract

BACKGROUND

Myanmar has prioritised people who inject drugs (PWID) as a key population for HIV mitigation efforts, with targets for needle and syringe distribution set at a population level. However, individual-level coverage, defined as the percentage of an individual's injecting episodes covered by a sterile syringe, is a more sensitive measure of intervention coverage. We sought to examine individual-level coverage in a sample of PWID in Myanmar.

METHODS

We recruited 512 PWID through urban drop-in-centres in Yangon, Mandalay and Pyin Oo Lwin. Participants were administered a quantitative questionnaire covering five domains: demographics, drug use, treatment and coverage, and injecting risk behaviour. We calculated past fortnight individual-level syringe coverage, estimating levels of sufficient (≥100% of injecting episodes covered by a sterile syringe) and insufficient (<100%) coverage, and examined associations between key variables and insufficient coverage via logistic regression.

RESULTS

Our sample was predominately male (97%), employed (76%), and living in stable accommodation (96%), with a median age of 27. All participants reported heroin as the drug most frequently injected, and injected a median of 27 times in the past two weeks. Nineteen per cent of participants had insufficient coverage in the two weeks before interview. Insufficient coverage was positively associated with syringe re-use (AOR: 5.19, 95% CIs: 2.57, 10.48) and acquiring sterile syringes from a location other than a formal drop-in-centre (AOR: 2.04, 95% CIs: 1.08, 3.82). Participants recruited in Mandalay (AOR: 0.30, 95% CIs: 0.11, 0.80) and Pyin Oo Lwin (AOR: 0.39, 95% CIs: 0.18, 0.87) had lower odds of insufficient coverage than those recruited in Yangon.

CONCLUSION

Our study shows coverage in selected areas of Myanmar was comparable with studies in other countries. Our results inform the delivery of harm reduction services for PWID, specifically by encouraging the use of formal drop-in-centres, over other sources of syringe distribution, such as pharmacies.

摘要

背景

缅甸将注射吸毒者(PWID)作为艾滋病毒缓解工作的重点人群,设定了在人群层面分发针具和注射器的目标。然而,个体层面的覆盖率(定义为无菌注射器覆盖个人注射次数的百分比)是衡量干预措施覆盖范围的更敏感指标。我们试图在缅甸的一组 PWID 样本中检查个体层面的覆盖率。

方法

我们通过仰光、曼德勒和彬乌伦的城市咨询中心招募了 512 名 PWID。参与者接受了涵盖五个领域的定量问卷:人口统计学、药物使用、治疗和覆盖范围以及注射风险行为。我们计算了过去两周的个体层面注射器覆盖率,估计了足够(无菌注射器覆盖的注射次数≥100%)和不足(<100%)的覆盖率,并通过逻辑回归检查了关键变量与不足覆盖率之间的关联。

结果

我们的样本主要由男性(97%)、有工作(76%)和居住在稳定住所(96%)组成,平均年龄为 27 岁。所有参与者均报告最常注射的药物是海洛因,过去两周内平均注射 27 次。19%的参与者在接受采访前两周的覆盖率不足。覆盖率不足与注射器重复使用(优势比:5.19,95%置信区间:2.57,10.48)和从非正规咨询中心以外的地点获得无菌注射器(优势比:2.04,95%置信区间:1.08,3.82)呈正相关。与在仰光招募的参与者相比,在曼德勒(优势比:0.30,95%置信区间:0.11,0.80)和彬乌伦(优势比:0.39,95%置信区间:0.18,0.87)招募的参与者不足的几率较低。

结论

我们的研究表明,在缅甸选定地区的覆盖率与其他国家的研究相当。我们的研究结果为为 PWID 提供减少伤害服务提供了信息,特别是鼓励使用正规咨询中心,而不是其他来源的注射器分发,如药店。

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