Rolfe M
Zambia Consolidated Copper Mines Ltd (Nkana division), Kitwe.
Diabet Med. 1988 Oct;5(7):630-3. doi: 10.1111/j.1464-5491.1988.tb01070.x.
Six hundred African diabetic patients were examined using a protocol based on the WHO Multinational study in which no country from Africa was represented. The salicylsulphonic acid test for proteinuria was used to assess the presence of diabetic renal disease. Overall 23.8% of patients had proteinuria (95% confidence interval 20.4 to 27.2) and 3.8% chronic renal failure (95% confidence interval 2.3 to 5.3). Patients with proteinuria were older and had had diabetes longer than those without (p less than 0.001). Systolic blood pressure rose with increasing proteinuria in both sexes but only men with severe nephropathy showed an increase in diastolic pressure. Minimal diabetic nephropathy was more common than severe nephropathy which carried a particularly poor prognosis in African diabetic patients due to lack of resources.
采用基于世界卫生组织多国研究的方案，对600名非洲糖尿病患者进行了检查，该研究中没有非洲国家参与。采用水杨磺酸蛋白尿试验来评估糖尿病肾病的存在情况。总体而言，23.8%的患者有蛋白尿（95%置信区间为20.4至27.2），3.8%有慢性肾衰竭（95%置信区间为2.3至5.3）。有蛋白尿的患者比没有蛋白尿的患者年龄更大，患糖尿病的时间更长（p<0.001）。男女患者的收缩压均随蛋白尿增加而升高，但只有重度肾病男性的舒张压升高。轻度糖尿病肾病比重度肾病更常见，由于资源匮乏，重度肾病在非洲糖尿病患者中预后特别差。
