Lunyera Joseph, Stanifer John W, Ingabire Prossie, Etolu Wilson, Bagasha Peace, Egger Joseph R, Patel Uptal D, Mutungi Gerald, Kalyesubula Robert
Duke Global Health Institute, Duke University, 310 Trent Drive, Durham, NC, USA.
School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
BMC Res Notes. 2016 Feb 16;9:97. doi: 10.1186/s13104-016-1897-6.
Despite the increasing prevalence of chronic kidney disease (CKD) in sub-Saharan Africa, few community-based screenings have been conducted in Uganda. Opportunities to improve the management of CKD in sub-Saharan Africa are limited by low awareness, inadequate access, poor recognition, and delayed presentation for clinical care. Therefore, the Uganda Kidney Foundation engaged key stakeholders in performing a screening event on World Kidney Day.
We conducted a cross-sectional pilot study in March 2013 from a convenience sample of adult, urban residents in Kampala, Uganda. We advertised the event using radio and television announcements, newspapers, billboards, and notice boards at public places, such as places of worship. Subsequently, we screened for proteinuria, hypertension, fasting glucose impairment, and obesity in a central and easily-accessible location.
We enrolled 141 adults most of whom were female (57 %), young (64 %; 18-39 years), and had a professional occupation (52 %). The prevalence of proteinuria (13 %; 95 % confidence interval [CI] 7-19 %), hypertension (38 %; 95 % CI 31-47 %), and impaired fasting glucose (13 %; 95 % CI 9-20 %) were high in this study population. Proteinuria was most prevalent among young (18-39 years) adults (n = 14; 16 %) and among those who reported a history of alcohol intake (n = 10; 32 %).
The prevalence of proteinuria was high among a convenience sample of urban residents in a sub-Saharan African setting. These results represent an important effort by the Ugandan Kidney Foundation to increase awareness and recognition of CKD, and they will help formulate additional epidemiological studies on NCDs in Uganda which are urgently needed and now feasible.
尽管撒哈拉以南非洲地区慢性肾脏病（CKD）的患病率不断上升，但乌干达很少开展基于社区的筛查。撒哈拉以南非洲地区改善CKD管理的机会受到认识不足、就医不便、识别能力差以及临床护理就诊延迟的限制。因此，乌干达肾脏基金会邀请主要利益相关者在世界肾脏日开展了一次筛查活动。
2013年3月，我们对乌干达坎帕拉市成年城市居民的便利样本进行了一项横断面试点研究。我们通过广播、电视公告、报纸、广告牌以及在公共场所（如礼拜场所）的布告栏宣传此次活动。随后，我们在一个中心且交通便利的地点筛查蛋白尿、高血压、空腹血糖受损和肥胖情况。
我们招募了141名成年人，其中大多数为女性（57%），年龄较轻（64%；18 - 39岁），且从事专业职业（52%）。该研究人群中蛋白尿（13%；95%置信区间[CI] 7 - 19%）、高血压（38%；95% CI 31 - 47%）和空腹血糖受损（13%；95% CI 9 - 20%）的患病率较高。蛋白尿在年轻（18 - 39岁）成年人中最为普遍（n = 14；16%），在有饮酒史的人群中也较为普遍（n = 10；32%）。
在撒哈拉以南非洲地区城市居民的便利样本中，蛋白尿患病率较高。这些结果是乌干达肾脏基金会提高对CKD认识和识别的一项重要举措，将有助于开展乌干达急需且目前可行的关于非传染性疾病的更多流行病学研究。
