Duba Ayyappa S, Mathew Stephanie D
Department of Rheumatology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA.
Department of Rheumatology, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA.
Prim Care. 2018 Jun;45(2):271-287. doi: 10.1016/j.pop.2018.02.005.
The seronegative spondyloarthropathies are a group of five diseases characterized by inflammatory oligoarticular arthritis, enthesitis, and axial involvement. They have an increased incidence of the HLA-B27 gene. They are commonly associated with extra-articular features including involvement of the skin, eyes, and gastrointestinal tract. Early recognition and referral are key to limit disability, and comanagement with primary care and rheumatology offers the best outcomes.
血清阴性脊柱关节病是一组五种疾病,其特征为炎性少关节炎、附着点炎和脊柱受累。它们的HLA - B27基因发生率增加。它们通常与关节外表现相关,包括皮肤、眼睛和胃肠道受累。早期识别和转诊是限制残疾的关键,与初级保健和风湿病学共同管理可带来最佳结果。