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辅助放疗在皮肤鳞状细胞癌中的价值:综述

The Value of Adjuvant Radiotherapy in Cutaneous Squamous Cell Carcinoma: A Review.

作者信息

Cañueto J, Jaka A, Toll A

机构信息

Servicio de Dermatología, Complejo Asistencial Universitario de Salamanca, IBSAL Instituto de Investigación Biomédica de Salamanca, Complejo Asistencial Universitario de Salamanca, Salamanca, España.

Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Badalona, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2018 Jul-Aug;109(6):476-484. doi: 10.1016/j.ad.2018.03.007. Epub 2018 May 24.

DOI:10.1016/j.ad.2018.03.007
PMID:29759308
Abstract

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans and its incidence is rising. Although surgery is the treatment of choice for cSCC, postoperative adjuvant radiotherapy has an important role in local and locorregional disease control. In this review, we analyze the value of postoperative radiotherapy in the management of high-risk cSCC (in particular, cases with perineural invasion), cSCC with positive surgical margins, and locally advanced cSCC (with parotid gland and/or lymph node metastasis).

摘要

皮肤鳞状细胞癌(cSCC)是人类第二常见的癌症,其发病率正在上升。虽然手术是cSCC的首选治疗方法,但术后辅助放疗在局部和区域疾病控制中具有重要作用。在本综述中,我们分析了术后放疗在高危cSCC(特别是伴有神经周围侵犯的病例)、手术切缘阳性的cSCC以及局部晚期cSCC(伴有腮腺和/或淋巴结转移)治疗中的价值。

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Clin Transl Oncol. 2024 Dec 19. doi: 10.1007/s12094-024-03826-5.
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MicroRNA-573 inhibits cell proliferation, migration and invasion and is downregulated by PICSAR in cutaneous squamous cell carcinoma.微小 RNA-573 抑制皮肤鳞状细胞癌中的细胞增殖、迁移和侵袭,并受 PICSAR 下调。
Bosn J Basic Med Sci. 2022 Apr 1;22(2):229-237. doi: 10.17305/bjbms.2021.6301.
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Radiotherapy in the Adjuvant and Advanced Setting of CSCC.
皮肤鳞状细胞癌辅助及晚期治疗中的放射疗法
Dermatol Pract Concept. 2021 Oct 1;11(Suppl 2):e2021168S. doi: 10.5826/dpc.11S2a168S. eCollection 2021 Nov.
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Adjuvant therapy for high-risk cutaneous squamous cell carcinoma: 10-year review.高危皮肤鳞状细胞癌的辅助治疗:10 年回顾。
Head Neck. 2021 Sep;43(9):2822-2843. doi: 10.1002/hed.26767. Epub 2021 Jun 7.
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