呼吁关注血液系统疾病：来自 ASH 血液学与衰老科学研讨会的报告。
A call to action in hematologic disorders: A report from the ASH scientific workshop on hematology and aging.
机构信息
The Ohio State University, Columbus, OH, United States.
University of California, San Francisco, CA, United States.
出版信息
J Geriatr Oncol. 2018 Jul;9(4):287-290. doi: 10.1016/j.jgo.2018.04.006. Epub 2018 May 16.
The American Society of Hematology (ASH) has recently promoted efforts to advance the intersection of hematology and aging by sponsoring an annual Scientific Friday Workshop on Hematology and Aging [1]. Hematologic disorders, both malignant and benign, are highly prevalent among older adults [–4]. Despite the disproportionate burden of hematologic disease among older adults [–5], research studying the implications of age across the translational spectrum remains limited older adults understudied [–8]. The lack of pre-clinical aging models, dearth of translational efforts across diseases, and under-enrollment of older adults in clinical trials result in substantial gaps in knowledge. Understanding the interface of human aging and hematologic disorders in a growing population of older adults is warranted. Here we outline the progress to date spearheaded by the ASH community dedicated to hematology and aging.
美国血液学会（ASH）最近通过赞助年度血液学与衰老科学星期五研讨会[1]，积极推动血液学和衰老领域的交叉发展。血液系统疾病，无论是恶性的还是良性的，在老年人中都非常普遍[–4]。尽管老年人中血液系统疾病的负担不成比例[–5]，但研究年龄在整个转化谱中的影响的研究仍然有限，老年人的研究不足[–8]。缺乏临床前衰老模型、疾病间转化工作的匮乏以及临床试验中老年人的参与不足，导致知识存在巨大缺口。在不断增长的老年人群体中，了解人类衰老和血液系统疾病之间的关系是必要的。在这里，我们概述了 ASH 社区在血液学和衰老领域的最新进展。
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