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1
Identification and Characterization of Salmonella enterica Serotype Newport Isolates with Decreased Susceptibility to Ciprofloxacin in the United States.美国对环丙沙星敏感性降低的肠炎沙门氏菌纽波特血清型分离株的鉴定和特性分析。
Antimicrob Agents Chemother. 2018 Jun 26;62(7). doi: 10.1128/AAC.00653-18. Print 2018 Jul.
2
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3
Presence of plasmid-mediated quinolone resistance determinants and mutations in gyrase and topoisomerase in Salmonella enterica isolates with resistance and reduced susceptibility to ciprofloxacin.对环丙沙星耐药和敏感性降低的肠炎沙门氏菌分离株中质粒介导的喹诺酮耐药决定子以及gyrase和拓扑异构酶中的突变情况。
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Co-occurrence of biofilm formation and quinolone resistance in Salmonella enterica serotype typhimurium carrying an IncHI2-type oqxAB-positive plasmid.产碳青霉烯酶阴沟肠杆菌中携带 IncHI2 型 oqxAB 阳性质粒的生物膜形成和喹诺酮耐药的共存。
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Quinolone Resistance Mechanisms Among Salmonella enterica in Malaysia.马来西亚肠炎沙门氏菌中的喹诺酮耐药机制
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Diverse phenotypic and genotypic characterization among clinical Klebsiella pneumoniae and Escherichia coli isolates carrying plasmid-mediated quinolone resistance determinants.携带质粒介导喹诺酮类耐药决定因子的临床肺炎克雷伯菌和大肠埃希菌分离株的表型和基因型特征多样化。
Microb Drug Resist. 2011 Sep;17(3):363-7. doi: 10.1089/mdr.2011.0034. Epub 2011 May 12.

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Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Serovars.血清型II型拓扑异构酶喹诺酮耐药决定区的突变多样性
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Diversified sources for human infections by Salmonella enterica serovar newport.人类感染沙门氏菌纽波特血清型的多种来源。
Transbound Emerg Dis. 2019 Mar;66(2):1044-1048. doi: 10.1111/tbed.13099. Epub 2019 Jan 7.

本文引用的文献

1
Identification of Plasmid-Mediated Quinolone Resistance in Salmonella Isolated from Swine Ceca and Retail Pork Chops in the United States.鉴定美国猪盲肠和零售猪排中分离出的沙门氏菌的质粒介导喹诺酮耐药性。
Antimicrob Agents Chemother. 2017 Sep 22;61(10). doi: 10.1128/AAC.01318-17. Print 2017 Oct.
2
Plasmid-mediated quinolone resistance in Enterobacteriaceae: a systematic review with a focus on Mediterranean countries.肠杆菌科细菌中质粒介导的喹诺酮耐药性：一项聚焦地中海国家的系统评价
Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):421-435. doi: 10.1007/s10096-016-2847-x. Epub 2016 Nov 26.
3
Increasing prevalence of ciprofloxacin-resistant food-borne Salmonella strains harboring multiple PMQR elements but not target gene mutations.携带多种质粒介导喹诺酮耐药（PMQR）元件但无靶基因突变的耐环丙沙星食源沙门氏菌菌株的流行率不断上升。
Sci Rep. 2015 Oct 5;5:14754. doi: 10.1038/srep14754.
4
Mechanisms of drug resistance: quinolone resistance.耐药机制：喹诺酮耐药性
Ann N Y Acad Sci. 2015 Sep;1354(1):12-31. doi: 10.1111/nyas.12830. Epub 2015 Jul 17.
5
Plasmid-mediated quinolone resistance in isolates of Salmonella enterica serotype Typhi, USA.美国伤寒沙门氏菌血清型 Typhi 分离株中的质粒介导喹诺酮耐药性
Int J Antimicrob Agents. 2015 Jan;45(1):88-90. doi: 10.1016/j.ijantimicag.2014.09.015. Epub 2014 Oct 24.
6
Characterization of blaCMY plasmids and their possible role in source attribution of Salmonella enterica serotype Typhimurium infections.blaCMY质粒的特征及其在鼠伤寒沙门氏菌感染源追踪中可能发挥的作用。
Foodborne Pathog Dis. 2014 Apr;11(4):301-6. doi: 10.1089/fpd.2013.1670. Epub 2014 Jan 31.
7
Prevalence of the oqxAB gene complex in Klebsiella pneumoniae and Escherichia coli clinical isolates.肺炎克雷伯菌和大肠埃希菌临床分离株中oqxAB基因复合体的流行情况。
J Antimicrob Chemother. 2012 Jul;67(7):1655-9. doi: 10.1093/jac/dks086. Epub 2012 Mar 21.
8
International collaborative study on the occurrence of plasmid-mediated quinolone resistance in Salmonella enterica and Escherichia coli isolated from animals, humans, food and the environment in 13 European countries.13 个欧洲国家的动物、人类、食物和环境中分离的食源性沙门氏菌和大肠杆菌中质粒介导的喹诺酮耐药性的国际协同研究。
J Antimicrob Chemother. 2011 Jun;66(6):1278-86. doi: 10.1093/jac/dkr084. Epub 2011 Mar 9.
9
Foodborne illness acquired in the United States--major pathogens.食源性疾病在美国的感染情况——主要病原体。
Emerg Infect Dis. 2011 Jan;17(1):7-15. doi: 10.3201/eid1701.p11101.
10
Plasmid-mediated quinolone resistance determinants in Salmonella spp. isolates from reptiles in Germany.德国爬行动物源沙门氏菌分离株中质粒介导的喹诺酮耐药决定因子
J Antimicrob Chemother. 2010 Sep;65(9):2043-5. doi: 10.1093/jac/dkq242. Epub 2010 Jul 1.

美国对环丙沙星敏感性降低的肠炎沙门氏菌纽波特血清型分离株的鉴定和特性分析。

Identification and Characterization of Salmonella enterica Serotype Newport Isolates with Decreased Susceptibility to Ciprofloxacin in the United States.

机构信息

Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

IHRC, Inc., Atlanta, Georgia, USA.

出版信息

Antimicrob Agents Chemother. 2018 Jun 26;62(7). doi: 10.1128/AAC.00653-18. Print 2018 Jul.

DOI:10.1128/AAC.00653-18
PMID:29760131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6021668/
Abstract

Nontyphoidal (NTS) causes an estimated 1.2 million illnesses, 23,000 hospitalizations, and 450 deaths each year in the United States. Decreased susceptibility to ciprofloxacin (DSC) has historically been associated with chromosomal mutations of the quinolone resistance determining region (QRDR), but plasmid-mediated quinolone resistance (PMQR) genes are increasing. To investigate DSC among serotype Newport strains, we examined 40 isolates from 1996 to 2016 with DSC. Thirty isolates (71%) contained the PMQR gene and eight isolates (19%) contained a QRDR.

摘要

在美国，非伤寒型（NTS）每年估计导致 120 万例疾病、2.3 万例住院和 450 例死亡。对环丙沙星的敏感性降低（DSC）历史上与喹诺酮类药物耐药决定区（QRDR）的染色体突变有关，但质粒介导的喹诺酮类耐药（PMQR）基因正在增加。为了研究血清型纽波特菌株中的 DSC，我们检测了 1996 年至 2016 年间 40 株具有 DSC 的分离株。30 株（71%）含有 PMQR 基因，8 株（19%）含有 QRDR。