Shigematsu Yasuyuki, Kanda Hiroaki, Nagasaki Toshiya, Ishizawa Takeaki, Inoue Yosuke, Takahashi Shunji
Department of Pathology, The Cancer Institute of Japanese Foundation for Cancer Research (JFCR), Japan.
Division of General Oncology, The Cancer Institute Hospital of JFCR, Japan.
Intern Med. 2018;57(10):1405-1409. doi: 10.2169/internalmedicine.0083-17. Epub 2018 May 15.
The clinical course of hepatic eosinophilic abscess (HEA) induced by malignant tumors is not well-known; however, it is considered to be a benign hepatic lesion. HEA is difficult to diagnose by imaging alone and a pathological examination is generally needed, particularly in patients with malignant tumors, because the radiological findings can be similar to those of metastasis. We report a case of multiple HEAs with eosinophilia and sigmoid colon cancer that was difficult to diagnose without a pathological examination. After the resection of the sigmoid colon cancer, the patient's eosinophilia was quickly ameliorated and the HEAs disappeared within 6 months.
恶性肿瘤所致肝嗜酸性脓肿(HEA)的临床病程尚不明确;然而,其被认为是一种良性肝脏病变。HEA仅通过影像学检查很难诊断,通常需要进行病理检查,尤其是对于患有恶性肿瘤的患者,因为其影像学表现可能与转移瘤相似。我们报告一例伴有嗜酸性粒细胞增多症的多发HEA合并乙状结肠癌患者,若不进行病理检查很难诊断。乙状结肠癌切除术后,患者的嗜酸性粒细胞增多症迅速改善,HEA在6个月内消失。